Greater efficacy of SPF 100+ sunscreen compared with SPF 50+ in sunburn prevention during 5 consecutive days of sunlight exposure: A randomized, double-blind clinical trial
Beach vacations are high-risk settings for overexposure to ultraviolet radiation. To compare the sunburn protective efficacy of SPF 50+ and SPF 100+ sunscreens under actual use at the beach. A prospective, randomized, double-blind, single-center, split-body/face study of 55 healthy individuals. Each...
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| Published in: | Journal of the American Academy of Dermatology Vol. 82; no. 4; pp. 869 - 877 |
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| Main Authors: | , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
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01-04-2020
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| Abstract | Beach vacations are high-risk settings for overexposure to ultraviolet radiation.
To compare the sunburn protective efficacy of SPF 50+ and SPF 100+ sunscreens under actual use at the beach.
A prospective, randomized, double-blind, single-center, split-body/face study of 55 healthy individuals. Each participant applied both sunscreens to randomized sides of the face/body for up to 5 consecutive days. Blinded clinical evaluation of erythema by a single grader and objective instrumental assessments, colorimetry, and diffuse reflectance spectroscopy were performed the morning after each sun exposure.
After 5 days, 31 (56%) participants had more sunburn on the SPF 50+ side compared to 4 (7%) on the SPF 100+ side. Overall, mean erythema intensity showed statistically significantly less erythema on the SPF 100+ side compared with the SPF 50+ side. The first observation of sunburn exclusively on the SPF 50+ side occurred after 1 day of sun exposure, whereas that for SPF 100+ occurred after 3 days of sun exposure.
Only initial sunscreen application was monitored, only 1 participant with skin phototype I was recruited, and participants were recruited from a local beach area.
SPF 100+ was significantly more effective in protecting against ultraviolet radiation–induced erythema and sunburn than SPF 50+ in actual use in a beach vacation setting. |
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| AbstractList | Beach vacations are high-risk settings for overexposure to ultraviolet radiation.
To compare the sunburn protective efficacy of SPF 50+ and SPF 100+ sunscreens under actual use at the beach.
A prospective, randomized, double-blind, single-center, split-body/face study of 55 healthy individuals. Each participant applied both sunscreens to randomized sides of the face/body for up to 5 consecutive days. Blinded clinical evaluation of erythema by a single grader and objective instrumental assessments, colorimetry, and diffuse reflectance spectroscopy were performed the morning after each sun exposure.
After 5 days, 31 (56%) participants had more sunburn on the SPF 50+ side compared to 4 (7%) on the SPF 100+ side. Overall, mean erythema intensity showed statistically significantly less erythema on the SPF 100+ side compared with the SPF 50+ side. The first observation of sunburn exclusively on the SPF 50+ side occurred after 1 day of sun exposure, whereas that for SPF 100+ occurred after 3 days of sun exposure.
Only initial sunscreen application was monitored, only 1 participant with skin phototype I was recruited, and participants were recruited from a local beach area.
SPF 100+ was significantly more effective in protecting against ultraviolet radiation-induced erythema and sunburn than SPF 50+ in actual use in a beach vacation setting. |
| Author | Atillasoy, Evren Lyons, Alexis B. Maitra, Prithwiraj Tian, Xiaoyan Williams, Joshua D. Seo, InSeok Nicholson, Cynthia L. Kohli, Indermeet Lim, Henry W. Hamzavi, Iltefat H. |
| Author_xml | – sequence: 1 givenname: Indermeet surname: Kohli fullname: Kohli, Indermeet organization: Department of Dermatology, Henry Ford Hospital, Detroit, Michigan – sequence: 2 givenname: Cynthia L. surname: Nicholson fullname: Nicholson, Cynthia L. organization: Department of Dermatology, Henry Ford Hospital, Detroit, Michigan – sequence: 3 givenname: Joshua D. surname: Williams fullname: Williams, Joshua D. organization: Johnson & Johnson Consumer Inc, Skillman, New Jersey – sequence: 4 givenname: Alexis B. surname: Lyons fullname: Lyons, Alexis B. organization: Department of Dermatology, Henry Ford Hospital, Detroit, Michigan – sequence: 5 givenname: InSeok surname: Seo fullname: Seo, InSeok organization: Johnson & Johnson Consumer Inc, Skillman, New Jersey – sequence: 6 givenname: Prithwiraj surname: Maitra fullname: Maitra, Prithwiraj organization: Johnson & Johnson Consumer Inc, Skillman, New Jersey – sequence: 7 givenname: Xiaoyan surname: Tian fullname: Tian, Xiaoyan organization: Johnson & Johnson Consumer Inc, Skillman, New Jersey – sequence: 8 givenname: Evren surname: Atillasoy fullname: Atillasoy, Evren organization: Johnson & Johnson Consumer Inc, Skillman, New Jersey – sequence: 9 givenname: Henry W. surname: Lim fullname: Lim, Henry W. organization: Department of Dermatology, Henry Ford Hospital, Detroit, Michigan – sequence: 10 givenname: Iltefat H. surname: Hamzavi fullname: Hamzavi, Iltefat H. email: Ihamzav1@hfhs.org organization: Department of Dermatology, Henry Ford Hospital, Detroit, Michigan |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31542406$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1038/jid.2010.95 10.1111/bjd.12211 10.1001/archderm.1988.01670060015008 10.1111/php.12085 10.1038/sj.jid.5700287 10.1001/archderm.144.11.1449 10.1016/j.jaad.2012.02.029 10.1080/19325037.2016.1271755 10.1038/sj.jid.5700417 10.1562/0031-8655(2001)073<0621:UDOA>2.0.CO;2 10.1001/jamadermatol.2016.4922 10.1016/j.jaad.2017.12.062 10.1016/j.jaad.2003.10.126 10.1111/php.12885 10.1016/j.jaad.2009.05.025 |
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| Keywords | a UV sunscreen sun protection factor DRS CI medical dermatology SPF UPF sunlight clinical research SPT beach vacation general dermatology prevention HbO2 |
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To compare the sunburn protective efficacy of SPF 50+ and SPF 100+ sunscreens... |
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| Title | Greater efficacy of SPF 100+ sunscreen compared with SPF 50+ in sunburn prevention during 5 consecutive days of sunlight exposure: A randomized, double-blind clinical trial |
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