Lack of ouabain effect on pacing-induced myocardial ischemia in patients with coronary artery disease

Sixteen patients with significant two and three vessel coronary artery disease but without clinical congestive heart failure were studied during rapid atrial pacing before and after infusion of 0.015 mg/kg of ouabain. Seven patients with a decreased (less than 50 percent) election fraction and nine...

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Bibliographic Details
Published in:	The American journal of cardiology Vol. 43; no. 5; pp. 995 - 1000
Main Authors:	Loeb, Henry S., Streitmatter, Nancy, Braunstein, David, Jacobs, William R., Croke, Robert P., Gunnar, Rolf M.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-05-1979
Subjects:	Adult Blood Pressure - drug effects Cardiac Pacing, Artificial Coronary Circulation - drug effects Coronary Disease - drug therapy Coronary Disease - metabolism Coronary Disease - physiopathology Electrocardiography Heart Conduction System - drug effects Heart Rate - drug effects Humans Infusions, Parenteral Lactates - metabolism Male Middle Aged Myocardial Contraction - drug effects Myocardium - metabolism Ouabain - administration & dosage Ouabain - therapeutic use Oxygen Consumption - drug effects Vascular Resistance - drug effects
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