Isohemigossypolone: Antiophidic properties of a naphthoquinone isolated from Pachira aquatica Aubl

We investigated the antiophidic properties of isohemigossypolone (ISO), a naphthoquinone isolated from the outer bark of the Pachira aquatic Aubl. The inhibition of phospholipase A2, coagulant, fibrinogenolytic, hemorrhagic and myotoxic activities induced by Bothrops pauloensis venom (Pb) was invest...

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Bibliographic Details
Published in:	Comparative biochemistry and physiology. Toxicology & pharmacology Vol. 245; p. 109028
Main Authors:	Vieira, Sâmela Alves Pereira Batista, dos Santos, Benedito Matheus, Santos Júnior, Célio Dias, de Paula, Vanderlúcia Fonseca, Gomes, Mario Sergio Rocha, Ferreira, Glaucio Monteiro, Gonçalves, Ricardo Lemes, Hirata, Mario Hiroyuki, da Silva, Roosevelt Alves, Brandeburgo, Maria Inês Homsi, Mendes, Mirian Machado
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-07-2021
Subjects:	Antiophidic Bothrops pauloensis Naphthoquinone Pachira aquatica Aubl Snake venom Antiophidic BthMP Snake venom ISO CK MHD PLA2 RMSD Bothrops pauloensis Pachira aquatica Aubl BmooMPα-I Pb MD EB Naphthoquinone
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