MWCNT-oxazolidinone conjugates with antibacterial activity

MWCNT-oxazolidinone conjugates with antibacterial activity

In this work, two types of MWCNT-oxazolidinone conjugates were synthesized, by varying the quartz tube lengths in the reactor (40 cm and 60 cm), with the aim at evaluating and comparing their biological potential against nine bacterial strains. MWCNT-1 (40 cm) showed higher surface defects and lower...

Full description

Saved in:
Bibliographic Details
Published in:Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology Vol. 22; no. 11
Main Authors: Moreno-Valle, Bibiana, Alatorre-Barajas, José A., Gochi-Ponce, Yadira, Alcántar-Zavala, Eleazar, Rivera-Lugo, Yazmín Yorely, Montes-Ávila, Julio, Trujillo-Navarrete, Balter, Alonso-Núñez, Gabriel, Reynoso-Soto, Edgar A., Ochoa-Terán, Adrián
Format: Journal Article
Language:English
Published: Dordrecht Springer Netherlands 01-11-2020
Springer Nature B.V
Subjects:
Antibacterial activity
Characterization and Evaluation of Materials
Chemical modification
Chemistry and Materials Science
Conjugates
Crystal defects
Inorganic Chemistry
Lasers
Materials Science
Nanomaterials
Nanoparticles
Nanotechnology
Optical Devices
Optics
Photonics
Physical Chemistry
Research Paper
Strains (organisms)
Surface defects
Surface stability
Antibacterial activity
Nanomaterials
Health effects
Oxazolidinone
MWCNT
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this work, two types of MWCNT-oxazolidinone conjugates were synthesized, by varying the quartz tube lengths in the reactor (40 cm and 60 cm), with the aim at evaluating and comparing their biological potential against nine bacterial strains. MWCNT-1 (40 cm) showed higher surface defects and lower crystallinity than MWCNT-2 (60 cm). During each step of chemical modification, the organic material incorporation onto the MWCNTs changed the surface defects, density, and thermic stability. Interestingly, due to the intrinsic antibacterial activity of the oxazolidinone compounds, oxazolidinone-conjugated nanomaterials f -MWCNT-S n - Oxa were active against the evaluated strains, while none of pristine MWCNT, f -MWCNT, or f -MWCNT-S n exhibited antibacterial activity. The results point out to f -MWCNT-S 1 - Oxa -1 as the best antibacterial nanomaterial because it was active against several bacterial strains. Antibacterial results obtained with the f -MWCNT-S n - Oxa -1 series demonstrate a significant effect of the oligomethylene chain (S n ) length against Staphylococcus aureus clinically isolated strain.
ISSN:1388-0764
1572-896X
DOI:10.1007/s11051-020-05044-w