The Diagnostic Value of Irisin and Visfatin in Experimental Testicular Torsion

• Published in: Haseki tıp bülteni Vol. 55; no. 4; pp. 274 - 279
• Main Authors: Saraç, Fatma, Yeniocak, Selman, Büyükbeşe Sarsu, Sevgi, Yücetaş, Esma, Olgaç, Vakur, Toptaş, Mehmet, Koldaş, Macit
• Format: Journal Article
• Language: English
• Published: Istanbul Haseki Eğitim ve Araştırma Hastanesi 01-12-2017; Galenos Publishing House; Galenos Yayinevi
• Subjects: Diabetes; experimental; Histopathology; irisin; Ischemia; Metabolism; Sağlık Hizmetleri; Statistical analysis; Studies; Testicular torsion; Tıp; visfatin; İstanbul; Türkiye; Istanbul Turkey; China; Turkey; Testicular torsion; Testis torsiyonu; experimental; irisin; deneysel; visfatin
• ISSN: 1302-0072; 2147-2688
• DOI: 10.4274/haseki.65375

Aim: Testicular torsion (TT) is one of the most important causes of
acute scrotum in children and young men. Very scarce number of
serum laboratory parameters might be used in the early diagnosis of
patients with TT. We planned this study in consideration of the possible
significance of the changes in serum irisin and visfatin levels in the
diagnosis of TT.
Methods: We used 28 rats in four groups. In the control group,
blood samples and specimens of testicular tissue were collected at
2nd and 4th hours after torsion. In the torsion groups, the left testis
was twisted, and blood samples and specimens of the testicular tissue
were collected at the 2nd and 4th hours for analysis.
Results: There was no statistically significant difference in mean irisin
and visfatin levels at the 2nd and 4th hours between rats with TT and
controls. There was no statistically difference between mean irisin and
vistatin levels at the 2nd hour and at the 4th hour in torsion and control
groups.
Conclusion: In our experimental TT method, we could not find a
statistically significant difference between serum levels of irisin and
visfatin. We assume that further studies are needed on this issue.