Schizencephaly with occlusion or absence of middle cerebral artery

• Published in: Neuroradiology Vol. 48; no. 3; pp. 171 - 175
• Main Authors: FERNANDEZ-BOUZAS, A, HARMONY, T, SANTIAGO-RODRIGUEZ, E, RICARDO-GARCELL, J, FERNANDEZ, T, AVILA-ACOSTA, D
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01-03-2006; Springer Nature B.V
• Subjects: Adult and adolescent clinical studies; Babies; Biological and medical sciences; Brain damage; Cardiovascular system; Central Nervous System Vascular Malformations - complications; Cerebral Cortex - abnormalities; Cerebral Ventricles - abnormalities; Female; Humans; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery - complications; Infarction, Middle Cerebral Artery - embryology; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Middle Cerebral Artery - abnormalities; Miscellaneous; Mood disorders; Nervous system; Neurology; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Subarachnoid Space - abnormalities; Veins & arteries; Perinatal risk factors; Nervous system diseases; Magnetic resonance angiography (MRA); Ischemia; Radiodiagnosis; Middle cerebral artery; Risk factor; Perinatal; Schizencephaly; Cardiovascular disease; NMR angiography; Middle cerebral artery (MCA)
• ISSN: 0028-3940; 1432-1920
• DOI: 10.1007/s00234-005-0006-7

In a study of 160 infants with prenatal and/or perinatal risk factors for brain damage, we observed three cases of schizencephaly. All cases were unilateral, and the clefts had open lips. In two cases, magnetic resonance angiography showed occlusion or absence of the middle cerebral artery (MCA) on the affected side. Two of the patients, including one with absent flow in the MCA of the affected side, had ipsilateral cerebellar atrophy.