Agomelatine could prevent brain and cerebellum injury against LPS-induced neuroinflammation in rats

•Neuroinflammation, oxidative stress, and apoptosis act in LPS-induced brain damage.•Agomelatine has antioxidant, antiinflammatory and antiapoptotic features.•Agomelatine effects on platelet count should be invesitigated in further studies. Sepsis, systemic hyper-inflammatory immune response, causes...

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Bibliographic Details
Published in:Cytokine (Philadelphia, Pa.) Vol. 127; p. 154957
Main Authors: Savran, M., Aslankoc, R., Ozmen, O., Erzurumlu, Y., Savas, H.B., Temel, E.N., Kosar, P.A., Boztepe, S.
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01-03-2020
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