Agomelatine could prevent brain and cerebellum injury against LPS-induced neuroinflammation in rats
•Neuroinflammation, oxidative stress, and apoptosis act in LPS-induced brain damage.•Agomelatine has antioxidant, antiinflammatory and antiapoptotic features.•Agomelatine effects on platelet count should be invesitigated in further studies. Sepsis, systemic hyper-inflammatory immune response, causes...
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Published in: | Cytokine (Philadelphia, Pa.) Vol. 127; p. 154957 |
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Main Authors: | , , , , , , , |
Format: | Journal Article |
Language: | English |
Published: |
England
Elsevier Ltd
01-03-2020
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Subjects: | |
Online Access: | Get full text |
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