The correlations between electroencephalogram frequency components and restoration of stable breathing from respiratory events in sleep apnea hypopnea syndrome

• Published in: Respiratory physiology & neurobiology Vol. 258; pp. 91 - 97
• Main Authors: Huang, Shaoxiong, Wang, Tingting, Zhang, Xiangmin, Yen, Chen-Wen, Liang, Jiuxing, Zeng, Lingzi, Luo, Yuxi
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01-12-2018
• Subjects: Respiratory physiology; Sleep apnea syndrome; Ventilatory control; Ventilatory control; Respiratory physiology; Sleep apnea syndrome
• ISSN: 1569-9048; 1878-1519
• DOI: 10.1016/j.resp.2018.06.006

•We explored the ways in which the EEG and SpO2 are involved in the respiratory restoration process.•Higher power of each EEG band and lower EEG complexity were relative to respiratory rhythm recovery.•Low EEG frequency bands were more relevant to the respiratory restoration.•EEG and SpO2 were independently related to the respiratory restoration.•A self-adjust function in EEG activity may be involved in the process of stable breathing restoration.
The purpose of this study was to explore the ways in which the Electroencephalogram (EEG) and oxygen saturation (SpO2) are involved in the progressive respiratory restoration process in patients with sleep apnea hypopnea syndrome (SAHS). Twenty-five SAHS patients were enrolled in the analysis. The respiratory events scored from polysomnography (PSG) recordings were divided into two groups as follows: the events followed by secondary events (SREs), which failed to recover stable breathing and those that spontaneously restored stable ventilation (N-SREs). The trends over the course from consecutive respiratory events (CRE) to stable breathing were also analyzed. Higher spectral powers of the δ, θ, and α bands and smaller sample entropy (SampEn) values in the EEG, along with a smaller SpO2 drop were observed in N-SREs, compared to those in SREs. It indicated there are correlations between these conditions and the restoration from respiratory events. The δ band power was the most relevant feature. In the CRE restoring process, the δ, θ, and α powers were significantly increased, while SampEn values exhibited the opposite tendency. Our results may reveal the relationship between EEG activity and respiratory rhythm control.