An overview of the optimal planning, design, and conduct of phase I studies of new therapeutics

Phase I clinical trials represent the first step in bringing promising new treatments from the laboratory to the clinic. Although the importance of phase I clinical trials is widely recognized, there is currently no consensus among the scientific, medical, and statistical communities on how best to...

Full description

Bibliographic Details

Published in:	Clinical cancer research Vol. 16; no. 6; pp. 1710 - 1718
Main Authors:	LoRusso, Patricia M, Boerner, Scott A, Seymour, Lesley
Format:	Journal Article
Language:	English
Published:	United States 15-03-2010
Subjects:	Antineoplastic Agents - therapeutic use Biomarkers, Tumor - analysis Clinical Trials, Phase I as Topic - methods Clinical Trials, Phase I as Topic - standards Humans Neoplasms - chemistry Neoplasms - drug therapy Practice Guidelines as Topic Research Design United States United States Food and Drug Administration United States
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!