Influence of bile acid derivates on morphine analgesic effect in mice

It is known that bile acids improve the absorption, bioavailability and pharmacodynamic characteristics of some drugs. Morphine analgesia is produced by activation of opioid receptors within the central nervous system (CNS) at both spinal and supraspinal levels. Since a morphine molecule contains 3...

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Bibliographic Details

Published in:	Vojnosanitetski pregled Vol. 71; no. 8; pp. 767 - 771
Main Authors:	Vasović, Velibor, Vukmirović, Sasa, Mikov, Momir, Mikov, Ivan, Budakov, Zorana, Stilinović, Nebojsa, Milijasević, Boris
Format:	Journal Article
Language:	English
Published:	Serbia Military Health Department, Ministry of Defance, Serbia 01-08-2014
Subjects:	Analgesics, Opioid - pharmacology Animals bile acids and salts blood-brain barrier Cholic Acids - pharmacology Disease Models, Animal Drug Interactions Male Mice morphine Morphine - pharmacology Pain - prevention & control
Online Access:	Get full text
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