Effect of Colchicine, Colcemid, and Vinblastine on the Agglutination, by Concanavalin A, of Transformed Cells

The sensitivity of transformed 3T3 fibroblasts to agglutination by concanavalin A is reduced by alkaloids that bind specifically to protein subunits of microtubules.

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Bibliographic Details
Published in:	Science (American Association for the Advancement of Science) Vol. 178; no. 4063; pp. 867 - 868
Main Authors:	Yin, Helen H., Ukena, Thomas E., Berlin, Richard D.
Format:	Journal Article
Language:	English
Published:	United States American Association for the Advancement of Science 24-11-1972
Subjects:	3T3 cells Agglutination Agglutination - drug effects Alkaloids Animals Binding sites Cell Line Cell Transformation, Neoplastic Colchicine - pharmacology Concanavalin A - antagonists & inhibitors Cultured cells Erythrocytes Erythrocytes - immunology Fibroblasts Hemadsorption Hemagglutination Lectins - antagonists & inhibitors Mice Microtubules Simian virus 40 T lymphocytes Vinblastine - pharmacology
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