Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders

Abstract FOXP transcription factors play important roles in neurodevelopment, but little is known about how their transcriptional activity is regulated. FOXP proteins cooperatively regulate gene expression by forming homo- and hetero-dimers with each other. Physical associations with other transcrip...

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Bibliographic Details

Published in:	Human molecular genetics Vol. 27; no. 7; pp. 1212 - 1227
Main Authors:	Estruch, Sara B, Graham, Sarah A, Quevedo, Martí, Vino, Arianna, Dekkers, Dick H W, Deriziotis, Pelagia, Sollis, Elliot, Demmers, Jeroen, Poot, Raymond A, Fisher, Simon E
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01-04-2018
Subjects:	Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism Gene Expression Regulation HEK293 Cells Humans Neurodevelopmental Disorders - genetics Neurodevelopmental Disorders - metabolism Neurodevelopmental Disorders - pathology Purkinje Cells - metabolism Purkinje Cells - pathology Repressor Proteins - genetics Repressor Proteins - metabolism Transcription Factors - genetics Transcription Factors - metabolism
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