Macrophage‐derived progranulin promotes allergen‐induced airway inflammation

Background Progranulin (PGRN), mainly produced by immune and epithelial cells, has been known to be involved in the development of various inflammatory diseases. However, the function of PGRN in allergic airway inflammation has not been clearly elucidated, and we investigated the role of PGRN in all...

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Bibliographic Details
Published in:	Allergy (Copenhagen) Vol. 75; no. 5; pp. 1133 - 1145
Main Authors:	Choi, Jun‐Pyo, Park, So Young, Moon, Keun‐Ai, Ha, Eun Hee, Woo, Yeon Duk, Chung, Doo Hyun, Kwon, Hyouk‐Soo, Kim, Tae‐Bum, Park, Hae‐Sim, Moon, Hee‐Bom, Song, Woo‐Jung, Cho, You Sook
Format:	Journal Article
Language:	English
Published:	Denmark Blackwell Publishing Ltd 01-05-2020
Subjects:	airway Allergens Allergies Alveoli Animal models Animals Asthma Bronchus Cell lines Cytokines Disease Models, Animal Epithelial cells house dust mite Hypersensitivity Hypersensitivity - immunology Immune response Inflammation Inflammatory diseases Lymphocytes T macrophage Macrophages Mice Natural killer cells progranulin Progranulins Pyroglyphidae Respiratory tract Respiratory tract diseases Rodents Th2 Cells Thymic stromal lymphopoietin progranulin macrophage house dust mite inflammation airway
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