Adverse reactions of ferric carboxymaltose

• Published in: Journal of clinical and diagnostic research Vol. 8; no. 10; pp. HD01 - HD02
• Main Authors: Thanusubramanian, Harish, Patil, Navin, Shenoy, Smita, Bairy, K L, Sarma, Yashdeep
• Format: Journal Article
• Language: English
• Published: India JCDR Research and Publications (P) Limited 01-10-2014; JCDR Research and Publications Private Limited
• Subjects: anemia; breathlessness; chronic kidney disease; Pharmacology Section; rft( renal function test); Breathlessness; RFT (renal function test); Chronic kidney disease; Anemia
• ISSN: 2249-782X; 0973-709X
• DOI: 10.7860/JCDR/2014/9499.5015

The author reports a 55-year-old female diagnosed of chronic kidney disease grade-5 with associated co-morbidities like type 2 diabetes mellitus, diabetic retinopathy and hypothyroidism was admitted for arteriovenous fistula construction. She was started on ferric carboxymaltose for the treatment of anaemia. She was given a test dose before administering the drug intravenously and she did not develop any reaction. The drug ferric carboxymaltose was then administered over a period of one hour. About half an hour after drug administration, the patient developed breathlessness and myalgia. After half hour of the above episode of breathlessness and myalgia she also developed vomiting (one episode). Patient was managed with oxygen therapy, IV fluids and other drugs like corticosteroids, phenaramine maleate and nalbuphine which controlled the above symptoms.