Probiotic supplementation containing Bacillus velezensis enhances expression of immune regulatory genes against pigeon circovirus in pigeons (Columba livia)

Aims In this study, we aimed to isolate and evaluate the efficacy of Bacillus velezensis as a probiotic and to assess its activity towards pigeons infected with pigeon circovirus (PiCV). Methods and Results Bacillus velezensis, isolated from pigeon faeces, was orally administered to pigeons for 60 d...

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Bibliographic Details
Published in:	Journal of applied microbiology Vol. 130; no. 5; pp. 1695 - 1704
Main Authors:	Tsai, C.‐Y., Hu, S.‐Y., Santos, H.M., Catulin, G.E.M., Tayo, L.L., Chuang, K.P.
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01-05-2021
Subjects:	Animals Antiviral Agents - pharmacology Bacillus Bacillus velezensis Bird Diseases - immunology Bird Diseases - virology Birds Circoviridae Infections - immunology Circoviridae Infections - veterinary Circovirus - drug effects Circovirus - immunology Columbidae - genetics Columbidae - immunology Columbidae - virology Cytokines - genetics Cytokines - metabolism Dietary Supplements - microbiology DNA, Viral Feces Feces - microbiology Gene expression Gene Expression Regulation Genes Immune response Immune system Immunity, Innate - genetics indicator genes Innate immunity Interferon Interferon-gamma Interleukins Myxovirus resistance proteins Oral administration pigeon circovirus Pigeons probiotic supplementation Probiotics Probiotics - pharmacology Spleen Stat1 protein Supplements TLR2 protein TLR4 protein Toll-like receptors Transcription factors Transducers Viral Load indicator genes pigeons pigeon circovirus probiotic supplementation Bacillus velezensis
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