Effects of dobutamine, dopamine, phenylephrine and noradrenaline on systemic haemodynamics and intestinal perfusion in isoflurane anaesthetised horses

Summary Background In the horse, effects of cardiovascular‐active drugs on local perfusion of the gastrointestinal tract are poorly understood. Objectives To determine the effect of drugs commonly used to support blood pressure, on local intestinal blood flow and tissue oxygenation under isoflurane...

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Bibliographic Details
Published in:	Equine veterinary journal Vol. 50; no. 1; pp. 104 - 110
Main Authors:	Dancker, C., Hopster, K., Rohn, K., Kästner, S. B.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01-01-2018
Subjects:	Adrenergic alpha-Agonists - administration & dosage Adrenergic alpha-Agonists - pharmacology Anesthesia Anesthesia, Inhalation - veterinary Anesthetics, Inhalation - administration & dosage Anesthetics, Inhalation - pharmacology Animals Blood flow Blood pressure Cardiac output Cardiotonic Agents - administration & dosage Cardiotonic Agents - pharmacology catecholamines Circulatory system Colon Cross-Over Studies Dobutamine - administration & dosage Dobutamine - pharmacology Dopamine Dopamine - administration & dosage Dopamine - pharmacology Doppler effect Drug dosages Female Gastrointestinal tract Heart diseases Heart rate Hemodynamics Hemodynamics - drug effects horse Horses Horses - physiology Intestine Intestines - blood supply Isoflurane Isoflurane - administration & dosage Isoflurane - pharmacology Jejunum Male Measurement techniques microcirculation Noradrenaline Norepinephrine Norepinephrine - administration & dosage Norepinephrine - pharmacology Oxygenation Perfusion Peripheral blood Phenylephrine Phenylephrine - administration & dosage Phenylephrine - pharmacology Randomization Remission Spectrophotometry splanchnic circulation Stomach Sulfur dioxide vasoconstrictor agents White light horse catecholamines vasoconstrictor agents splanchnic circulation microcirculation
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