Continuous local anesthetic infusion for pain management after outpatient inguinal herniorrhaphy

The purpose of the present study is to compare postoperative pain and functional outcomes in patients undergoing inguinal herniorrhaphy who receive a continuous wound infusion of bupivacaine to those who receive an infusion of saline. A prospective, randomized, blinded, placebo-controlled trial was...

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Published in:Surgery Vol. 136; no. 4; pp. 761 - 769
Main Authors: Schurr, Michael J., Gordon, Debra B., Pellino, Teresa A., Scanlon, Trisha A.
Format: Journal Article
Language:English
Published: United States Mosby, Inc 01-10-2004
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Abstract The purpose of the present study is to compare postoperative pain and functional outcomes in patients undergoing inguinal herniorrhaphy who receive a continuous wound infusion of bupivacaine to those who receive an infusion of saline. A prospective, randomized, blinded, placebo-controlled trial was conducted in adults undergoing outpatient inguinal herniorrhaphy. Patients received saline or bupivacaine through a disposable infusion pump for 60 hours postoperatively. Pain outcomes were assessed, as were functional outcomes (activity, return of bowel function) and side effects. On postoperative day 1, patients who received bupivacaine had lower ratings for worst pain than patients who received saline, (5.0 ± 2.3 vs 6.7 ± 2.2, P = .002). On day 1, least pain ratings were also lower, and patients ambulated more frequently than those who received placebo. There were no differences between groups from postoperative days 2 to 5. There were no differences between groups in the amount of hydrocodone consumption. Continuous infusion of local anesthetic after inguinal herniorrhaphy provides modest improvements in pain scores and functional outcomes when compared with placebo. However, these effects are limited to the first postoperative day only. The additional costs associated with this intervention may limit its widespread use in clinical practice.
AbstractList The purpose of the present study is to compare postoperative pain and functional outcomes in patients undergoing inguinal herniorrhaphy who receive a continuous wound infusion of bupivacaine to those who receive an infusion of saline. A prospective, randomized, blinded, placebo-controlled trial was conducted in adults undergoing outpatient inguinal herniorrhaphy. Patients received saline or bupivacaine through a disposable infusion pump for 60 hours postoperatively. Pain outcomes were assessed, as were functional outcomes (activity, return of bowel function) and side effects. On postoperative day 1, patients who received bupivacaine had lower ratings for worst pain than patients who received saline, (5.0 ± 2.3 vs 6.7 ± 2.2, P = .002). On day 1, least pain ratings were also lower, and patients ambulated more frequently than those who received placebo. There were no differences between groups from postoperative days 2 to 5. There were no differences between groups in the amount of hydrocodone consumption. Continuous infusion of local anesthetic after inguinal herniorrhaphy provides modest improvements in pain scores and functional outcomes when compared with placebo. However, these effects are limited to the first postoperative day only. The additional costs associated with this intervention may limit its widespread use in clinical practice.
The purpose of the present study is to compare postoperative pain and functional outcomes in patients undergoing inguinal herniorrhaphy who receive a continuous wound infusion of bupivacaine to those who receive an infusion of saline. A prospective, randomized, blinded, placebo-controlled trial was conducted in adults undergoing outpatient inguinal herniorrhaphy. Patients received saline or bupivacaine through a disposable infusion pump for 60 hours postoperatively. Pain outcomes were assessed, as were functional outcomes (activity, return of bowel function) and side effects. On postoperative day 1, patients who received bupivacaine had lower ratings for worst pain than patients who received saline, (5.0 +/- 2.3 vs 6.7 +/- 2.2, P=.002). On day 1, least pain ratings were also lower, and patients ambulated more frequently than those who received placebo. There were no differences between groups from postoperative days 2 to 5. There were no differences between groups in the amount of hydrocodone consumption. Continuous infusion of local anesthetic after inguinal herniorrhaphy provides modest improvements in pain scores and functional outcomes when compared with placebo. However, these effects are limited to the first postoperative day only. The additional costs associated with this intervention may limit its widespread use in clinical practice.
BACKGROUNDThe purpose of the present study is to compare postoperative pain and functional outcomes in patients undergoing inguinal herniorrhaphy who receive a continuous wound infusion of bupivacaine to those who receive an infusion of saline.METHODSA prospective, randomized, blinded, placebo-controlled trial was conducted in adults undergoing outpatient inguinal herniorrhaphy. Patients received saline or bupivacaine through a disposable infusion pump for 60 hours postoperatively. Pain outcomes were assessed, as were functional outcomes (activity, return of bowel function) and side effects.RESULTSOn postoperative day 1, patients who received bupivacaine had lower ratings for worst pain than patients who received saline, (5.0 +/- 2.3 vs 6.7 +/- 2.2, P=.002). On day 1, least pain ratings were also lower, and patients ambulated more frequently than those who received placebo. There were no differences between groups from postoperative days 2 to 5. There were no differences between groups in the amount of hydrocodone consumption.CONCLUSIONSContinuous infusion of local anesthetic after inguinal herniorrhaphy provides modest improvements in pain scores and functional outcomes when compared with placebo. However, these effects are limited to the first postoperative day only. The additional costs associated with this intervention may limit its widespread use in clinical practice.
Author Schurr, Michael J.
Scanlon, Trisha A.
Pellino, Teresa A.
Gordon, Debra B.
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  givenname: Trisha A.
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/15467660$$D View this record in MEDLINE/PubMed
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Snippet The purpose of the present study is to compare postoperative pain and functional outcomes in patients undergoing inguinal herniorrhaphy who receive a...
BACKGROUNDThe purpose of the present study is to compare postoperative pain and functional outcomes in patients undergoing inguinal herniorrhaphy who receive a...
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SubjectTerms Adult
Ambulatory Surgical Procedures
Anesthetics, Local - administration & dosage
Biocompatible Materials - therapeutic use
Bupivacaine - administration & dosage
Double-Blind Method
Female
Hernia, Inguinal - surgery
Humans
Infusion Pumps
Male
Middle Aged
Pain Measurement
Pain, Postoperative - drug therapy
Polypropylenes - therapeutic use
Prospective Studies
Recovery of Function
Surgical Mesh
Title Continuous local anesthetic infusion for pain management after outpatient inguinal herniorrhaphy
URI https://dx.doi.org/10.1016/j.surg.2004.06.016
https://www.ncbi.nlm.nih.gov/pubmed/15467660
https://search.proquest.com/docview/66944730
Volume 136
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