Synthesis and applications of graphene oxide aerogels in bone tissue regeneration: a review

• Published in: Materials today chemistry Vol. 20; p. 100422
• Main Authors: Berrio, M.E., Oñate, A., Salas, A., Fernández, K., Meléndrez, M.F.
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01-06-2021
• Subjects: Aerogels; Bone tissue regeneration; Graphene oxide aerogels; Scaffold; Aerogels; Bone tissue regeneration; Scaffold; Graphene oxide aerogels
• ISSN: 2468-5194; 2468-5194
• DOI: 10.1016/j.mtchem.2021.100422

Development of biocompatible porous supports is a promising strategy in the field of tissue engineering for the repair and regeneration of bone tissues with severe damage. Graphene oxide aerogels (GOAs) are excellent candidates for the manufacture of these systems due to their porosity, ability to imitate bone structure, and mechanical resistance, and according to their surface chemical reactivity, they can facilitate osseointegration, osteogenesis, osteoinduction and osteoconduction. In this review, synthesis of GOAs from the most primary source is described, and recent studies on the use of these functionalized carbonaceous foams as scaffolding for bone tissue regeneration are presented.
•The potential applications in the biomedical field of graphene oxide aerogels.•The main methods of graphene oxide aerogels obtaining and properties, are compiled.•The regeneration of bone tissue are highlighted, mainly focused on graphene oxide aerogels and it's optimal conditions of osseointegration, osteogenesis, osteoinduction and osteoconduction.