Optimizing Drug Delivery of Small-Volume Infusions
When administering intermittent secondary intravenous infusions, commonly referred to as intravenous piggyback (IVPB) infusions, residual medication remains in the administration set and bag. No previous studies exist examining the optimal technique to infuse the residual medication. The aims of thi...
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| Published in: | Journal of infusion nursing Vol. 41; no. 2; pp. 113 - 117 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Language: | English |
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Copyright by Infusion Nurses Society
01-03-2018
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| Abstract | When administering intermittent secondary intravenous infusions, commonly referred to as intravenous piggyback (IVPB) infusions, residual medication remains in the administration set and bag. No previous studies exist examining the optimal technique to infuse the residual medication. The aims of this study were to identify various IVPB ancillary techniques used to administer medication residing in the secondary administration set and bag following an infusion, evaluate the potential drug loss associated with each technique, and recommend a standard ancillary technique for administration of select small-volume IVPB infusions. Qualitative and quantitative tests were performed, leading to a recommendation for a standard ancillary technique for select small-volume IVPB infusions. |
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| AbstractList | When administering intermittent secondary intravenous infusions, commonly referred to as intravenous
piggyback
(IVPB) infusions, residual medication remains in the administration set and bag. No previous studies exist examining the optimal technique to infuse the residual medication. The aims of this study were to identify various IVPB ancillary techniques used to administer medication residing in the secondary administration set and bag following an infusion, evaluate the potential drug loss associated with each technique, and recommend a standard ancillary technique for administration of select small-volume IVPB infusions. Qualitative and quantitative tests were performed, leading to a recommendation for a standard ancillary technique for select small-volume IVPB infusions. When administering intermittent secondary intravenous infusions, commonly referred to as intravenous piggyback (IVPB) infusions, residual medication remains in the administration set and bag. No previous studies exist examining the optimal technique to infuse the residual medication. The aims of this study were to identify various IVPB ancillary techniques used to administer medication residing in the secondary administration set and bag following an infusion, evaluate the potential drug loss associated with each technique, and recommend a standard ancillary technique for administration of select small-volume IVPB infusions. Qualitative and quantitative tests were performed, leading to a recommendation for a standard ancillary technique for select small-volume IVPB infusions. |
| Author | Piddoubny, Maria Ednalino, Ryan Terry, Colin L Thoele, Kelli |
| AuthorAffiliation | Indiana University Health, Indianapolis, Indiana (Ms Thoele, Dr Ednalino, and Mr Terry); and Thomas Jefferson University Hospital, Philadelphia, Pennsylvania (Dr Piddoubny). Kelli Thoele, MSN, RN, ACNS-BC, BMTCN®, OCN®, is a clinical nurse specialist at Indiana University Health in Indianapolis, Indiana. She is interested in evidence-based practice and safe handling of hazardous drugs. Maria Piddoubny, PharmD, BCOP, is a PGY-2 graduate of Indiana University Health in Indianapolis, Indiana, now working as a hematology/oncology patient care pharmacist at Thomas Jefferson University Hospital in Philadelphia, Pennsylvania. Her interests include chemotherapy medication safety and translational research in oncology genomics. Ryan Ednalino, PharmD, is a medication safety clinical pharmacist for Indiana University Health. He oversees medication safety initiatives across the multifacility hospital system. He serves on pharmacy and therapeutics and multiple system medication safety committees. C |
| AuthorAffiliation_xml | – name: Indiana University Health, Indianapolis, Indiana (Ms Thoele, Dr Ednalino, and Mr Terry); and Thomas Jefferson University Hospital, Philadelphia, Pennsylvania (Dr Piddoubny). Kelli Thoele, MSN, RN, ACNS-BC, BMTCN®, OCN®, is a clinical nurse specialist at Indiana University Health in Indianapolis, Indiana. She is interested in evidence-based practice and safe handling of hazardous drugs. Maria Piddoubny, PharmD, BCOP, is a PGY-2 graduate of Indiana University Health in Indianapolis, Indiana, now working as a hematology/oncology patient care pharmacist at Thomas Jefferson University Hospital in Philadelphia, Pennsylvania. Her interests include chemotherapy medication safety and translational research in oncology genomics. Ryan Ednalino, PharmD, is a medication safety clinical pharmacist for Indiana University Health. He oversees medication safety initiatives across the multifacility hospital system. He serves on pharmacy and therapeutics and multiple system medication safety committees. Colin L. Terry, MS, is a biostatistician and serves as program manager for data services at Indiana University Health in Indianapolis, Indiana. He consults and collaborates on a wide variety of research projects and serves on several institutional boards as a lead statistical reviewer |
| Author_xml | – sequence: 1 givenname: Kelli surname: Thoele fullname: Thoele, Kelli organization: Indiana University Health, Indianapolis, Indiana (Ms Thoele, Dr Ednalino, and Mr Terry); and Thomas Jefferson University Hospital, Philadelphia, Pennsylvania (Dr Piddoubny). Kelli Thoele, MSN, RN, ACNS-BC, BMTCN®, OCN®, is a clinical nurse specialist at Indiana University Health in Indianapolis, Indiana. She is interested in evidence-based practice and safe handling of hazardous drugs. Maria Piddoubny, PharmD, BCOP, is a PGY-2 graduate of Indiana University Health in Indianapolis, Indiana, now working as a hematology/oncology patient care pharmacist at Thomas Jefferson University Hospital in Philadelphia, Pennsylvania. Her interests include chemotherapy medication safety and translational research in oncology genomics. Ryan Ednalino, PharmD, is a medication safety clinical pharmacist for Indiana University Health. He oversees medication safety initiatives across the multifacility hospital system. He serves on pharmacy and therapeutics and multiple system medication safety committees. Colin L. Terry, MS, is a biostatistician and serves as program manager for data services at Indiana University Health in Indianapolis, Indiana. He consults and collaborates on a wide variety of research projects and serves on several institutional boards as a lead statistical reviewer – sequence: 2 givenname: Maria surname: Piddoubny fullname: Piddoubny, Maria – sequence: 3 givenname: Ryan surname: Ednalino fullname: Ednalino, Ryan – sequence: 4 givenname: Colin surname: Terry middlename: L fullname: Terry, Colin L |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29489706$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1002/ajh.24228 10.1016/S0140-6736(05)67110-3 10.2146/ajhp080434 10.1093/jac/43.4.601 |
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| References | Aminzadeh (R5-20230822) 2014; 7 Rybak (R4-20230822) 2009; 66 Tavitian (R2-20230822) 2016; 91 Colleoni (R3-20230822) 2005; 366 Gorski (R8-20230822) 2016; 39 Sevinç (R1-20230822) 1999; 43 |
| References_xml | – volume: 91 start-page: 193 issue: 2 year: 2016 ident: R2-20230822 article-title: Impact of obesity in favorable‐risk AML patients receiving intensive chemotherapy publication-title: Am J Hematol doi: 10.1002/ajh.24228 contributor: fullname: Tavitian – volume: 366 start-page: 1108 issue: 9491 year: 2005 ident: R3-20230822 article-title: Relation between chemotherapy dose, oestrogen receptor expression, and body-mass index publication-title: Lancet doi: 10.1016/S0140-6736(05)67110-3 contributor: fullname: Colleoni – volume: 66 start-page: 82 issue: 1 year: 2009 ident: R4-20230822 article-title: Therapeutic monitoring of vancomycin in adult patients: a consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists publication-title: Am J Health Syst Pharm doi: 10.2146/ajhp080434 contributor: fullname: Rybak – volume: 43 start-page: 601 issue: 4 year: 1999 ident: R1-20230822 article-title: Early switch from intravenous to oral antibiotics: guidelines and implementation in a large teaching hospital publication-title: J Antimicrob Chemother doi: 10.1093/jac/43.4.601 contributor: fullname: Sevinç – volume: 7 start-page: e12831 issue: 10 year: 2014 ident: R5-20230822 article-title: Vancomycin minimum inhibitory concentration for methicillin-resistant Staphylococcus aureus infections; is there difference in mortality between patients? publication-title: Jundishapur J Microbiol contributor: fullname: Aminzadeh – volume: 39 start-page: S1 issue: suppl 1 year: 2016 ident: R8-20230822 article-title: Infusion therapy standards of practice publication-title: J Infus Nurs contributor: fullname: Gorski |
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| Snippet | When administering intermittent secondary intravenous infusions, commonly referred to as intravenous piggyback (IVPB) infusions, residual medication remains in... When administering intermittent secondary intravenous infusions, commonly referred to as intravenous piggyback (IVPB) infusions, residual medication remains in... |
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| SubjectTerms | Humans Infusions, Intravenous - instrumentation Infusions, Intravenous - methods Infusions, Intravenous - nursing Nursing Pharmaceutical Preparations |
| Title | Optimizing Drug Delivery of Small-Volume Infusions |
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