Enhanced visualization of axonopathy in EAE using thy1-YFP transgenic mice

Abstract It is widely accepted that chronic disabilities in multiple sclerosis (MS) patients are due in part to neuronal damage. The central aim of this study was to characterize axonal disruption in the spinal cord of mice with myelin oligodendrocyte glycoprotein-induced experimental autoimmune enc...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of the neurological sciences Vol. 260; no. 1; pp. 23 - 32
Main Authors:	Bannerman, P.G, Hahn, A
Format:	Journal Article
Language:	English
Published:	Shannon Elsevier B.V 15-09-2007 Elsevier Science
Subjects:	Animals Antibodies, Monoclonal - immunology Antibody Specificity - immunology Axonopathy Axons - immunology Axons - pathology Biological and medical sciences CD11 Antigens - immunology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Encephalomyelitis, Autoimmune, Experimental - immunology Encephalomyelitis, Autoimmune, Experimental - pathology Encephalomyelitis, Autoimmune, Experimental - physiopathology Experimental autoimmune encephalomelitis (EAE) Genes, Reporter - genetics Immunohistochemistry Luminescent Proteins - immunology Medical sciences Mice Mice, Inbred C57BL Mice, Transgenic Motor neuron (MN) Motor Neurons - immunology Motor Neurons - metabolism Motor Neurons - pathology Multiple sclerosis (MS) Multiple Sclerosis - immunology Multiple Sclerosis - pathology Multiple Sclerosis - physiopathology Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Myelitis - immunology Myelitis - pathology Myelitis - physiopathology Neurofilament Proteins - immunology Neurofilament Proteins - metabolism Neurology Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - immunology Spinal Cord - immunology Spinal Cord - pathology Spinal Cord - physiopathology Staining and Labeling - methods Thy-1 Antigens - genetics Thy-1 Antigens - immunology Wallerian Degeneration - immunology Wallerian Degeneration - pathology Wallerian Degeneration - physiopathology Experimental autoimmune encephalomelitis (EAE) Axonopathy Multiple sclerosis (MS) Motor neuron (MN) Autoimmunity Visualization Multiple sclerosis Nervous system diseases Rodentia Motor neuron Inflammatory disease Vertebrata Mammalia Mouse Animal Central nervous system disease
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!