Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome C under stresses

Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome C under stresses

Herein, we present a simple approach to fabricate protein nanoconstructs by complexing cytochrome (Cyt ) with silk nanofibrils (SNF) and choline dihydrogen phosphate ionic liquid (IL). The peroxidase activity of the IL modified Cyt nanoconstruct (Cyt + SNF + IL) increased significantly (2.5 to 10-fo...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) Vol. 59; no. 39; p. 5894
Main Authors: Thayallath, Sarath Kumar, Shet, Sachin M, Bisht, Meena, Bharadwaj, Pranav, Pereira, Matheus M, Franklin, Gregory, Nataraj, S K, Mondal, Dibyendu
Format: Journal Article
Language:English
Published: England 11-05-2023
Subjects:
Cytochromes c - metabolism
Ionic Liquids
Online Access:Get more information
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Summary:Herein, we present a simple approach to fabricate protein nanoconstructs by complexing cytochrome (Cyt ) with silk nanofibrils (SNF) and choline dihydrogen phosphate ionic liquid (IL). The peroxidase activity of the IL modified Cyt nanoconstruct (Cyt + SNF + IL) increased significantly (2.5 to 10-fold) over unmodified Cyt and showed enhanced catalytic activity and stability under harsh conditions, proving its potential as a suitable protein packaging strategy.
ISSN:1364-548X
DOI:10.1039/d3cc00644a