Effect of cucurbitacins on bilirubin–albumin binding in human plasma

The aim of this study is to investigate the effect of three cucurbitacins (Cuc) E, D and I on the bilirubin–albumin binding, both in human serum albumin (HSA) and in plasma. Bilirubin–HSA solution and plasma free of cucurbitacins were prepared as well as others containing serial concentrations of cu...

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Bibliographic Details
Published in:	Life sciences (1973) Vol. 80; no. 6; pp. 579 - 585
Main Authors:	Greige-Gerges, H., Abou Khalil, R., Chahine, R., Haddad, C., Harb, W., Ouaini, N.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Inc 16-01-2007
Subjects:	Albumin Bilirubin Bilirubin - blood Bilirubin - metabolism Cucurbitacin Dose-Response Relationship, Drug Human plasma Humans Hyperbilirubinemia - blood Hyperbilirubinemia - metabolism Protein Binding - drug effects Serum Albumin - metabolism Triterpenes - pharmacology Albumin Cucurbitacin Human plasma Bilirubin
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