A multi-interpenetrating network (IPN) hydrogel with gelatin and silk fibroin

A multi-interpenetrating network (IPN) hydrogel with gelatin and silk fibroin

A mechanically strong composite hydrogel was produced based on an interpenetrating network (IPN) between gelatin and silk fibroin. When two layers of the IPN were created, the resulting hydrogel exhibited much improved mechanical properties. This hydrogel is biodegradable and non-cytotoxic and allow...

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Bibliographic Details
Published in:Biomaterials science Vol. 7; no. 4; p. 1276
Main Authors: Park, Shiwha, Edwards, Seth, Hou, Shujie, Boudreau, Ryann, Yee, Rachel, Jeong, Kyung Jae
Format: Journal Article
Language:English
Published: England 26-03-2019
Subjects:
Cell Adhesion
Cell Proliferation
Fibroblasts - cytology
Fibroins - chemistry
Gelatin - chemistry
Humans
Hydrogels - chemical synthesis
Hydrogels - chemistry
Particle Size
Silk - chemistry
Skin - cytology
Surface Properties
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Summary:A mechanically strong composite hydrogel was produced based on an interpenetrating network (IPN) between gelatin and silk fibroin. When two layers of the IPN were created, the resulting hydrogel exhibited much improved mechanical properties. This hydrogel is biodegradable and non-cytotoxic and allows for cell adhesion and proliferation on the surface.
ISSN:2047-4849
DOI:10.1039/c8bm01532e