Thromboembolic disease in pregnancy

Venous thromboembolic disease is a major cause of maternal morbidity and mortality. Virchow's triad of hypercoagulability, venous stasis, and vascular damage all occur during pregnancy. The risk of venous thromboembolism is five to six times higher during pregnancy and the puerperium. Risk fact...

Full description

Saved in:

Bibliographic Details
Published in:	Obstetrics and gynecology clinics of North America Vol. 31; no. 2; p. 319
Main Authors:	Doyle, Nora M, Monga, Manju
Format:	Journal Article
Language:	English
Published:	United States 01-06-2004
Subjects:	Anticoagulants - therapeutic use Female Genetic Predisposition to Disease Humans Pregnancy Pregnancy Complications, Cardiovascular - diagnosis Pregnancy Complications, Cardiovascular - therapy Prenatal Care Thrombophilia - diagnosis Thrombophilia - genetics Thrombophilia - therapy
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Venous thromboembolic disease is a major cause of maternal morbidity and mortality. Virchow's triad of hypercoagulability, venous stasis, and vascular damage all occur during pregnancy. The risk of venous thromboembolism is five to six times higher during pregnancy and the puerperium. Risk factors include age greater than 35, antiphospholipid antibodies, inherited thrombophilias, operative delivery, increased parity, obesity, mechanical heart valves,and family history. Prophylactic and therapeutic anticoagulation is recommended for women at risk. Low molecular weight heparins are safe and effective in most cases.
ISSN:	0889-8545
DOI:	10.1016/j.ogc.2004.03.008