In vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity of Murraya koenigii leaf extract intercedes ZnO nanoparticles

Nanotechnology is an emerging field with tremendous potential and usage of medicinal plants and green preparation of nanoparticles (NPs) is one of the widely explored areas. These have been shown to be effective against different biological activities such as diabetes mellitus, cancer, antioxidant,...

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Published in:Luminescence (Chichester, England) Vol. 38; no. 7; pp. 1139 - 1148
Main Authors: Sharma, Avinash, Nagraik, Rupak, Venkidasamy, Baskar, Khan, Azhar, Dulta, Kanika, Kumar Chauhan, Pankaj, Kumar, Deepak, Shin, Dong‐Soo
Format: Journal Article
Language:English
Published: England Wiley Subscription Services, Inc 01-07-2023
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Abstract Nanotechnology is an emerging field with tremendous potential and usage of medicinal plants and green preparation of nanoparticles (NPs) is one of the widely explored areas. These have been shown to be effective against different biological activities such as diabetes mellitus, cancer, antioxidant, antimicrobial, etc. The current studies focus on the green synthesis of zinc NPs (ZnO NPs) from aqueous leaf extract of Murraya koenigii (MK). The synthesized Murraya koeingii zinc oxide NPs (MK ZnO NPs) were characterized using UV–visible spectroscopy, dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy‐dispersive spectrum (EDS) and cyclic voltammetry (CV). The synthesized MK ZnO NPs were evaluated for their in vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity. They demonstrated significant antidiabetic and cytotoxic activity, as well as moderate free‐radical scavenging and antibacterial activity. Murraya koeingii zinc oxide nanoparticles (MK ZnONPs) prepared via green synthesis, characterized and evaluated for their biological activities. The particle showed significant anti‐diabetic and cytotoxic activity, as well as moderate free‐radical scavenging and antibacterial activity.
AbstractList Nanotechnology is an emerging field with tremendous potential and usage of medicinal plants and green preparation of nanoparticles (NPs) is one of the widely explored areas. These have been shown to be effective against different biological activities such as diabetes mellitus, cancer, antioxidant, antimicrobial, etc. The current studies focus on the green synthesis of zinc NPs (ZnO NPs) from aqueous leaf extract of Murraya koenigii (MK). The synthesized Murraya koeingii zinc oxide NPs (MK ZnO NPs) were characterized using UV–visible spectroscopy, dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy‐dispersive spectrum (EDS) and cyclic voltammetry (CV). The synthesized MK ZnO NPs were evaluated for their in vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity. They demonstrated significant antidiabetic and cytotoxic activity, as well as moderate free‐radical scavenging and antibacterial activity.
Nanotechnology is an emerging field with tremendous potential and usage of medicinal plants and green preparation of nanoparticles (NPs) is one of the widely explored areas. These have been shown to be effective against different biological activities such as diabetes mellitus, cancer, antioxidant, antimicrobial, etc. The current studies focus on the green synthesis of zinc NPs (ZnO NPs) from aqueous leaf extract of Murraya koenigii (MK). The synthesized Murraya koeingii zinc oxide NPs (MK ZnO NPs) were characterized using UV-visible spectroscopy, dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy-dispersive spectrum (EDS) and cyclic voltammetry (CV). The synthesized MK ZnO NPs were evaluated for their in vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity. They demonstrated significant antidiabetic and cytotoxic activity, as well as moderate free-radical scavenging and antibacterial activity.
Nanotechnology is an emerging field with tremendous potential and usage of medicinal plants and green preparation of nanoparticles (NPs) is one of the widely explored areas. These have been shown to be effective against different biological activities such as diabetes mellitus, cancer, antioxidant, antimicrobial, etc. The current studies focus on the green synthesis of zinc NPs (ZnO NPs) from aqueous leaf extract of Murraya koenigii (MK). The synthesized Murraya koeingii zinc oxide NPs (MK ZnO NPs) were characterized using UV–visible spectroscopy, dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy‐dispersive spectrum (EDS) and cyclic voltammetry (CV). The synthesized MK ZnO NPs were evaluated for their in vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity. They demonstrated significant antidiabetic and cytotoxic activity, as well as moderate free‐radical scavenging and antibacterial activity. Murraya koeingii zinc oxide nanoparticles (MK ZnONPs) prepared via green synthesis, characterized and evaluated for their biological activities. The particle showed significant anti‐diabetic and cytotoxic activity, as well as moderate free‐radical scavenging and antibacterial activity.
Author Venkidasamy, Baskar
Dulta, Kanika
Sharma, Avinash
Nagraik, Rupak
Kumar, Deepak
Khan, Azhar
Kumar Chauhan, Pankaj
Shin, Dong‐Soo
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  surname: Sharma
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  surname: Venkidasamy
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  surname: Khan
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  organization: Shoolini University
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  givenname: Kanika
  surname: Dulta
  fullname: Dulta, Kanika
  organization: Shoolini University
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  givenname: Pankaj
  surname: Kumar Chauhan
  fullname: Kumar Chauhan, Pankaj
  email: chauhanbiochem84@gmail.com
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  givenname: Deepak
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  organization: Shoolini University
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  givenname: Dong‐Soo
  surname: Shin
  fullname: Shin, Dong‐Soo
  organization: Changwon National University
BackLink https://www.ncbi.nlm.nih.gov/pubmed/35362206$$D View this record in MEDLINE/PubMed
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Keywords Murraya koenigii
antibacterial and cytotoxic activity
green synthesis
zinc oxide nanoparticles
antidiabetic activity
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Snippet Nanotechnology is an emerging field with tremendous potential and usage of medicinal plants and green preparation of nanoparticles (NPs) is one of the widely...
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SubjectTerms Analytical methods
Antibacterial activity
antibacterial and cytotoxic activity
Antibiotics
antidiabetic activity
Antioxidants
Biological effects
Cancer
Cytotoxicity
Diabetes mellitus
Electron microscopy
Field emission microscopy
Field emission spectroscopy
Fourier transforms
green synthesis
Herbal medicine
Infrared spectroscopy
Leaves
Light scattering
Medicinal plants
Murraya koenigii
Nanoparticles
Nanotechnology
Photon correlation spectroscopy
Plant extracts
Scanning electron microscopy
Scavenging
Spectroscopy
Synthesis
Zinc
Zinc oxide
zinc oxide nanoparticles
Title In vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity of Murraya koenigii leaf extract intercedes ZnO nanoparticles
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fbio.4244
https://www.ncbi.nlm.nih.gov/pubmed/35362206
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