Bioactive compounds of Aegle marmelos L., medicinal values and its food applications: A critical review

• Published in: Phytotherapy research Vol. 35; no. 4; pp. 1887 - 1907
• Main Authors: Venthodika, Anshid, Chhikara, Navnidhi, Mann, Sandeep, Garg, Mukesh Kumar, Sofi, Sajad Ahmad, Panghal, Anil
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01-04-2021; Wiley Subscription Services, Inc
• Subjects: Aegle - chemistry; Aegle marmelos; Antidiabetics; antifertility activity; Antiinfectives and antibacterials; Antioxidants; Bark; Bibliometrics; Bioactive compounds; Biocompatibility; Biological activity; Carotenoids; Clinical trials; coumarins; Degenerative diseases; Diabetes mellitus; Diet Therapy - methods; Fibers; Flavonoids; Food; Food industry; Food processing; Food processing industry; Food production; Fruit trees; Fruits; Functional foods & nutraceuticals; Herbal Medicine - methods; Humans; In vivo methods and tests; Lipid peroxidation; Lipids; medicinal; Nutrition; Oxidation; Oxidation resistance; Peroxidation; Pharmacology; Phenols; Plant Extracts - chemistry; Processing industry; Scavenging; Terpenes; Toxicity; Ulcerative colitis; waste utilization; antifertility activity; carotenoids; medicinal; waste utilization; coumarins
• ISSN: 0951-418X; 1099-1573
• DOI: 10.1002/ptr.6934

Aegle marmelos L. (bael) is a fruit tree of Rutaceae family, widely grown all over the world. This plant is gaining popularity because of its nutrient‐rich fruits and immense traditional medicinal usage and pharmacological properties. The health promotive and protective effect of bael fruit is accounted by fibers, carotenoids, phenolics, terpenoids, coumarins, flavonoids, and alkaloids. The curative relevance of these compounds has been assessed by various in vivo and in vitro studies. Fruit shows numerous possible health benefits, namely, radio‐protective effects, peroxidation, antibacterial, inhibition of lipid, antidiarrheal, gastroprotective, antiviral, antidiabetic, anti‐ulcerative colitis, cardioprotective, free‐radical scavenging (antioxidant) and hepatoprotective effects. The health benefits of bael are not only limited to edible portion (fruit), but it also extends to nonedible portion (root, trunk, bark, leaf, flower and seed) having comparable biologically active compounds. Increasing awareness about the role of diet among health‐conscious consumers for human well‐being has increased the interest in functional foods thereby exploration of the functional attributes of various underutilized plants is being reaffirmed and various sources are emerged out as suitable food material for processing industry. The various scientific reports collected from different bibliometric sources suggested that A. marmelos and its bioactive constituents could play a vital role in the prevention of several chronic and degenerative diseases associated with oxidation stress. This review emphasis on recent scientific evidences on nutrition and bioactive profile of A. marmelos, health benefits along with clinical and nonclinical trials of various phytoconstituents and A. marmelos potential in food processing industry for various food products. Our study suggests that this plant does indeed have pharmacological properties of interest, however, further extensive research is needed to establish a potential strategy that can balance the pharmacological and toxic effects of bael.