Epidemiology and pathogenesis of scleroderma

SUMMARY Scleroderma is a heterogenous connective tissue disorder characterized by fibrosis of the skin, with or without internal organ involvement. The aetiology of scleroderma may involve both environmental and genetic factors. Abnormalities involving the immune system, vascular tissue and extracel...

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Bibliographic Details
Published in:	Australasian journal of dermatology Vol. 44; no. 1; pp. 1 - 7
Main Authors:	Chen, Keng, See, Adrian, Shumack, Stephen
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Science Pty 01-02-2003 Blackwell
Subjects:	Biological and medical sciences connective tissue environment fibrosis genetics Humans immune system localized scleroderma Medical sciences microchimerism morphoea Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Scleroderma, Localized - epidemiology Scleroderma, Localized - etiology Scleroderma, Localized - immunology Scleroderma, Systemic - epidemiology Scleroderma, Systemic - etiology Scleroderma, Systemic - immunology systemic sclerosis Human Connective tissue disease Skin disease Pathogenesis Circumscribed scleroderma Review Epidemiology Connective tissue localized scleroderma systemic sclerosis morphoea Fibrosis Environment Genetics microchimerism Immune system
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