Expression and purification of human interferon alpha 2a (IFNα2a) in the methylotrophic yeast Pichia pastoris

Human interferon alpha 2a (IFNα2a) is a secreted glycoprotein that exerts a wide spectrum of biological effects, such as triggering of antiviral, antitumor and immunosuppressive responses. IFNα2a is used as pharmaceutical polypeptide in chronic hepatitis C virus (HCV) infection, chronic myelogenous...

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Bibliographic Details

Published in:	Protein expression and purification Vol. 211; p. 106339
Main Authors:	Chronopoulou, Sofia, Tsochantaridis, Ilias, Tokamani, Maria, Kokkinopliti, Kerasina Despoina, Tsomakidis, Petros, Giannakakis, Antonis, Galanis, Alex, Pappa, Aglaia, Sandaltzopoulos, Raphael
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-11-2023
Subjects:	A549 HT29 IFNα2a Interferon stimulated genes (ISGs) Pichia pastoris IFNα2a HT29 Interferon stimulated genes (ISGs) Pichia pastoris A549
Online Access:	Get full text
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