Different immortalized keratinocyte cell lines display distinct capabilities to differentiate and reconstitute an epidermis in vitro

Dermatological research relies on the availability of suitable models that most accurately reflect the in vivo situation. Primary keratinocytes obtained from skin reduction surgeries are not only limited by availability but have a short lifespan and show donor‐specific variations, which hamper the u...

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Bibliographic Details
Published in:	Experimental dermatology Vol. 33; no. 1; pp. e14985 - n/a
Main Authors:	Jahn, Magdalena, Lang, Victoria, Diehl, Sandra, Back, Robin, Kaufmann, Roland, Fauth, Torsten, Buerger, Claudia
Format:	Journal Article
Language:	English
Published:	Denmark Wiley Subscription Services, Inc 01-01-2024
Subjects:	Cell culture Cell Differentiation Cell Line Cell lines Chromosome aberrations Contact inhibition differentiation Epidermis Humans immortalized keratinocytes Keratinocytes Keratinocytes - metabolism Life span Oncogene Proteins, Viral - metabolism reconstituted epidermal models Telomerase reverse transcriptase reconstituted epidermal models immortalized keratinocytes differentiation
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