SinoNasal Microbiota Transfer to treat recalcitrant chronic rhinosinusitis: A case series

Key points SinoNasal Microbiota Transfer (SNMT) was safe with immediate benefit in all recipients, with sustained improvement in two of three recipients for up to 180 days. The addition of antimicrobial photodynamic therapy worsened chronic rhinosinusitis. These promising SNMT results warrant furthe...

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Bibliographic Details
Published in:	International forum of allergy & rhinology Vol. 14; no. 8; pp. 1386 - 1390
Main Authors:	Gill, Sandeep K., Hernaiz‐Leonardo, Juan C., Edens, Thaddeus J., Pascual, Athenea, Tang, Chris, Fan, Judy, Thamboo, Andrew, Mullings, Warren, Alsaleh, Saad, Alim, Bader M., Javer, Amin R., Manges, Amee R.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01-08-2024
Subjects:	Adult Aged Chronic Disease chronic rhinosinusitis experimental therapy Female Humans Male microbiome microbiome therapy Microbiota Middle Aged mucus transplant Paranasal Sinuses - microbiology Photodynamic therapy Rhinitis - microbiology Rhinitis - therapy Rhinosinusitis sinusitis Sinusitis - microbiology Sinusitis - therapy Treatment Outcome chronic rhinosinusitis sinusitis experimental therapy microbiome mucus transplant microbiome therapy
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Summary:	Key points SinoNasal Microbiota Transfer (SNMT) was safe with immediate benefit in all recipients, with sustained improvement in two of three recipients for up to 180 days. The addition of antimicrobial photodynamic therapy worsened chronic rhinosinusitis. These promising SNMT results warrant further study of safety and efficacy.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Report-3 ObjectType-Case Study-4
ISSN:	2042-6976 2042-6984 2042-6984
DOI:	10.1002/alr.23352