Helicobacter pylori in allergic and non-allergic rhinitis does play a protective or causative role?

• Published in: European archives of oto-rhino-laryngology Vol. 277; no. 1; pp. 141 - 145
• Main Authors: Akiner, Umur, Yener, H. Murat, Gozen, E. Deniz, Kuzu, S. Burcu, Canakcioglu, Salih
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 2020
• Subjects: Adolescent; Adult; Aged; Child; Child, Preschool; Cross-Sectional Studies; Female; Head and Neck Surgery; Helicobacter Infections - immunology; Helicobacter Infections - microbiology; Helicobacter pylori - immunology; Helicobacter pylori - isolation & purification; Humans; Male; Medicine; Medicine & Public Health; Middle Aged; Neurosurgery; Otorhinolaryngology; Rhinitis - immunology; Rhinitis - microbiology; Rhinology; Young Adult; Prevalence; Rhinitis; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Rhinitis, Allergic, Perennial; Hygiene hypothesis; Cross-sectional studies; Epidemiology; Eosinophils; Helicobacter pylori
• ISSN: 0937-4477; 1434-4726
• DOI: 10.1007/s00405-019-05659-3

Purpose
Many studies have investigated the effect of
Helicobacter pylori
(
H. pylori
) colonization on the development of allergic diseases, but with conflicting results. The purpose of this cross-sectional observation study is to estimate
H. pylori
prevalence in allergic and nonallergic nasal conditions and compare with normal population.
Methods
274 patients were tested for
H. pylori
with stool antigen test. Patients were compared with the control group for
H. pylori
positivity rates after they were categorized according to their primary diagnoses as mite allergy, pollen allergy, mite and pollen allergy, and non-allergic rhinitis with eosinophilic syndrome (NARES). Results were also classified according to age.
Results
The number of
H. pylori
-positive patients with mite allergy, mite and pollen allergy, and NARES were significantly higher than the control group in sadults. The percentages of patients in the pediatric group who had mite allergy, pollen allergy, mite and pollen allergy, or NARES were not significantly different when compared to the control group.
Conclusion
Forthcoming studies would undoubtedly evaluate of the profits of treating allergic nasal conditions by treating the aforementioned bacterial infection.