Quality-of-life evaluation for patients submitted to nasal endoscopic surgery for resection of pituitary tumours

• Published in: European archives of oto-rhino-laryngology Vol. 278; no. 5; pp. 1411 - 1418
• Main Authors: Dolci, Ricardo Landini Lutaif, de Moraes, Lígia Tédde, de Carvalho, Ana Carolina Mayor, Rickli, Jeniffer Cristina Kozechen, de Souza, Jamile Lopes, Encinas, Williams Escalante, Junior, José Viana Lima, Scalissi, Nilza Maria, dos Santos, Américo Rubens Leite, Lazarini, Paulo Roberto
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01-05-2021
• Subjects: Endoscopy; Head and Neck Surgery; Humans; Medicine; Medicine & Public Health; Neurosurgery; Otorhinolaryngology; Pituitary Neoplasms - surgery; Prospective Studies; Quality of Life; Rhinology; Treatment Outcome; Skull base; Quality-of-life; Pituitary adenoma; Patient health questionnaire; Hypophyse
• ISSN: 0937-4477; 1434-4726
• DOI: 10.1007/s00405-020-06381-1

Purpose
This study aimed to evaluate the pre- and post-operative quality-of-life of patients submitted to the resection of pituitary adenoma via endoscopic transsphenoidal.
Methods
This was a prospective study on patients submitted to endoscopic transsphenoidal pituitary surgery with the harvest of a nasoseptal flap who responded to the questionnaires FV-36 and SNOT-22 in the pre-operative and in months 1, 3 and 6 following the surgical procedure.
Results
A total of 42 patients submitted to pituitary adenoma resection surgery via endoscopic transsphenoidal with a nasoseptal flap were recruited. In all of the physical and mental domains (SF-36) evaluated, there was an improvement in the long-term evaluation (6 months), compared to the pre-operative, as well as in the site-specific evaluation (SNOT-22)
.
Conclusion
The global and site-specific questionnaires in the 6th post-operative month follow-up presented an important improvement in all the physical and mental domains evaluated, as well as in nasal function in the perception of the patients submitted to pituitary adenoma resection via endoscopic transsphenoidal, demonstrating the safety and efficiency of the procedure.