Complete clinical response of liver metastasis after chemotherapy:To resect or not?

Complete clinical response of liver metastasis after chemotherapy:To resect or not?

This paper aims to update the therapeutical strategies in liver metastasis with complete clinical response(CCR) after chemotherapy and to determine if surgery is always necessary after CCR.The aim of chemotherapy is to achieve a good clinical response rather than CCR of liver metastasis.The CCR of l...

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Bibliographic Details
Published in:World journal of gastrointestinal oncology Vol. 3; no. 7; pp. 107 - 110
Main Author: Jose M Ramia-Angel Roberto De la Plaza Jose E Quiones
Format: Journal Article
Language:English
Published: China Baishideng Publishing Group Co., Limited 15-07-2011
Subjects:
Chemotherapy
Clinical
Liver
Metastasis
response
Surgery
Chemotherapy
Metastasis
Clinical response
Liver
Surgery
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Summary:This paper aims to update the therapeutical strategies in liver metastasis with complete clinical response(CCR) after chemotherapy and to determine if surgery is always necessary after CCR.The aim of chemotherapy is to achieve a good clinical response rather than CCR of liver metastasis.The CCR of liver metastasis after chemotherapy cannot be considered synonymous with a cure.The resection of the hepatic segment where there was hepatic metastases with CCR after chemotherapy theoretically prevents recurrence,improves survival and makes it possible to conf irm whether there has been a complete pathological response.However,the medical literature about this topic is scarce and sometimes contradictory.
Bibliography:Jose M Ramia-Angel,Roberto De la Plaza,Jose E Quiones,HPB Surgical Unit,Department of Surgery,Universitary Hospital of Guadalajara,Guadalajara 19002,Spain
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Correspondence to: Jose M Ramia-Angel, MD, PhD, HPB Surgical Unit, Department of Surgery, Universitary Hospital of Guadalajara, Guadalajara 19002, Spain. jose_ramia@hotmail.com
Author contributions: Ramia-Angel JM wrote the paper; Ramia-Angel JM, De la Plaza R and Quiñones JE designed the research and did the bibliographical review.
Telephone: +34-915-336470 Fax: +34-949-209200
ISSN:1948-5204
1948-5204
DOI:10.4251/wjgo.v3.i7.107