Carbohydrate sulfotransferases: a review of emerging diagnostic and prognostic applications
Carbohydrate sulfotransferases (CHST) catalyse the biosynthesis of proteoglycans that enable physical interactions and signalling between different neighbouring cells in physiological and pathological states. The study aim was to provide an overview of emerging diagnostic and prognostic applications...
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| Published in: | Biochemia medica Vol. 33; no. 3; pp. 030503 - 265 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Language: | English |
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Croatia
Medicinska naklada
15-10-2023
Croatian Society of Medical Biochemistry and Laboratory Medicine |
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| Abstract | Carbohydrate sulfotransferases (CHST) catalyse the biosynthesis of proteoglycans that enable physical interactions and signalling between different neighbouring cells in physiological and pathological states. The study aim was to provide an overview of emerging diagnostic and prognostic applications of CHST. PubMed database search was conducted using the keywords "carbohydrate sulfotransferase" together with appropriate inclusion and exclusion criteria, whereby 41 publications were selected. Additionally, 40 records on CHST genetic and biochemical properties were hand-picked from UniProt, GeneCards, InterPro, and neXtProt databases. Carbohydrate sulfotransferases have been applied mainly in diagnostics of connective tissue disorders, cancer and inflammations. The lack of CHST activity was found in congenital connective tissue disorders while CHST overexpression was detected in different malignancies. Mutations of
gene cause skeletal dysplasia, chondrodysplasia, and autosomal recessive multiple joint dislocations while increased tissue expression of
,
and
is an unfavourable prognostic factor in ovarian cancer, glioblastoma and pancreatic cancer, respectively. Recently,
and
overexpression in the vascular smooth muscle cells was linked to the severe lung pathology in COVID-19 patients. Promising CHST diagnostic and prognostic applications have been described but larger clinical studies and robust analytical procedures are required for the more reliable diagnostic performance estimations. |
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| AbstractList | Carbohydrate sulfotransferases (CHST) catalyse the biosynthesis of proteoglycans that enable physical interactions and signalling between different neighbouring cells in physiological and pathological states. The study aim was to provide an overview of emerging diagnostic and prognostic applications of CHST. PubMed database search was conducted using the keywords "carbohydrate sulfotransferase" together with appropriate inclusion and exclusion criteria, whereby 41 publications were selected. Additionally, 40 records on CHST genetic and biochemical properties were hand-picked from UniProt, GeneCards, InterPro, and neXtProt databases. Carbohydrate sulfotransferases have been applied mainly in diagnostics of connective tissue disorders, cancer and inflammations. The lack of CHST activity was found in congenital connective tissue disorders while CHST overexpression was detected in different malignancies. Mutations of
gene cause skeletal dysplasia, chondrodysplasia, and autosomal recessive multiple joint dislocations while increased tissue expression of
,
and
is an unfavourable prognostic factor in ovarian cancer, glioblastoma and pancreatic cancer, respectively. Recently,
and
overexpression in the vascular smooth muscle cells was linked to the severe lung pathology in COVID-19 patients. Promising CHST diagnostic and prognostic applications have been described but larger clinical studies and robust analytical procedures are required for the more reliable diagnostic performance estimations. Carbohydrate sulfotransferases (CHST) catalyse the biosynthesis of proteoglycans that enable physical interactions and signalling between different neighbouring cells in physiological and pathological states. The study aim was to provide an overview of emerging diagnostic and prognostic applications of CHST. PubMed database search was conducted using the keywords “carbohydrate sulfotransferase” together with appropriate inclusion and exclusion criteria, whereby 41 publications were selected. Additionally, 40 records on CHST genetic and biochemical properties were hand-picked from UniProt, GeneCards, InterPro, and neXtProt databases. Carbohydrate sulfotransferases have been applied mainly in diagnostics of connective tissue disorders, cancer and inflammations. The lack of CHST activity was found in congenital connective tissue disorders while CHST overexpression was detected in different malignancies. Mutations of CHST3 gene cause skeletal dysplasia, chondrodysplasia, and autosomal recessive multiple joint dislocations while increased tissue expression of CHST11 , CHST12 and CHST15 is an unfavourable prognostic factor in ovarian cancer, glioblastoma and pancreatic cancer, respectively. Recently, CHST11 and CHST15 overexpression in the vascular smooth muscle cells was linked to the severe lung pathology in COVID-19 patients. Promising CHST diagnostic and prognostic applications have been described but larger clinical studies and robust analytical procedures are required for the more reliable diagnostic performance estimations. Carbohydrate sulfotransferases (CHST) catalyse the biosynthesis of proteoglycans that enable physical interactions and signalling between different neighbouring cells in physiological and pathological states. The study aim was to provide an overview of emerging diagnostic and prognostic applications of CHST. PubMed database search was conducted using the keywords “carbohydrate sulfotransferase” together with appropriate inclusion and exclusion criteria, whereby 41 publications were selected. Additionally, 40 records on CHST genetic and biochemical properties were hand-picked from UniProt, GeneCards, InterPro, and neXtProt databases. Carbohydrate sulfotransferases have been applied mainly in diagnostics of connective tissue disorders, cancer and inflammations. The lack of CHST activity was found in congenital connective tissue disorders while CHST overexpression was detected in different malignancies. Mutations of CHST3 gene cause skeletal dysplasia, chondrodysplasia, and autosomal recessive multiple joint dislocations while increased tissue expression of CHST11, CHST12 and CHST15 is an unfavourable prognostic factor in ovarian cancer, glioblastoma and pancreatic cancer, respectively. Recently, CHST11 and CHST15 overexpression in the vascular smooth muscle cells was linked to the severe lung pathology in COVID-19 patients. Promising CHST diagnostic and prognostic applications have been described but larger clinical studies and robust analytical procedures are required for the more reliable diagnostic performance estimations. |
| Author | Debeljak, Željko Marković, Ivana Begolli, Gramos Knežević, Jelena |
| Author_xml | – sequence: 1 givenname: Gramos surname: Begolli fullname: Begolli, Gramos organization: Clinic of medical biochemistry, University clinical center of Kosovo, Prishtina, Kosovo – sequence: 2 givenname: Ivana surname: Marković fullname: Marković, Ivana organization: Faculty of medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia – sequence: 3 givenname: Jelena surname: Knežević fullname: Knežević, Jelena organization: Faculty for dental medicine and health, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia – sequence: 4 givenname: Željko surname: Debeljak fullname: Debeljak, Željko organization: Faculty of medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/37545696$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1093/rheumatology/keu478 10.1158/0008-5472.CAN-09-1378 10.18632/oncotarget.27634 10.1007/s10620-016-4114-5 10.1038/79987 10.1021/bi020507h 10.1111/cge.12885 10.3390/cells11152400 10.1073/pnas.0400334101 10.1038/s41420-020-00320-z 10.1002/ijc.25704 10.1159/000519542 10.1146/annurev-bioeng-071516-044610 10.1007/s10620-019-05530-9 10.1007/s00216-012-5944-4 10.1002/cam4.5186 10.1002/jcp.20450 10.1111/jcmm.16440 10.1111/cge.12694 10.1080/21655979.2021.1944455 10.1186/s12891-022-05719-6 10.1097/MCD.0000000000000021 10.1016/j.bbagen.2012.02.001 10.1016/j.jpba.2021.114339 10.1016/j.ajhg.2009.11.010 10.3892/ol.2017.6071 10.3390/ijms20133331 10.1096/fasebj.11.4.9068609 10.1016/S1074-5521(99)80014-3 10.1021/cb2004466 10.1038/s41598-019-46896-0 10.1007/s13277-015-3652-3 10.1515/cclm-2017-1157 10.1016/j.phrs.2018.08.011 10.1016/j.thromres.2017.11.016 10.3389/fimmu.2020.00512 10.1016/bs.mcb.2016.03.001 |
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| Keywords | cancer tumour markers connective tissue inflammation carbohydrate sulfotransferases |
| Language | English |
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| References | Zhang (key20230726050507_r12) 2020; 10 Debeljak (key20230726050507_r73) 2018; 56 Zheng (key20230726050507_r11) 2020; 6 key20230726050507_r29 key20230726050507_r28 key20230726050507_r27 key20230726050507_r26 key20230726050507_r25 Showe (key20230726050507_r74) 2009; 69 Wight (key20230726050507_r8) 2020; 11 Hennet (key20230726050507_r62) 2012; 1820 Grunwell (key20230726050507_r1) 2002; 41 Falany (key20230726050507_r4) 1997; 11 Zhou (key20230726050507_r68) 2016; 61 Ranza (key20230726050507_r56) 2017; 91 Oliveira-Ferrer (key20230726050507_r72) 2015; 36 Takakura (key20230726050507_r9) 2019; 20 key20230726050507_r24 key20230726050507_r23 Ren (key20230726050507_r69) 2021; 205 McKee (key20230726050507_r6) 2019; 9 key20230726050507_r22 key20230726050507_r21 Kausar (key20230726050507_r55) 2022; 23 key20230726050507_r20 key20230726050507_r19 key20230726050507_r18 key20230726050507_r17 key20230726050507_r16 key20230726050507_r15 key20230726050507_r14 Searle (key20230726050507_r59) 2014; 23 Dong (key20230726050507_r75) 2022; 11 Bi (key20230726050507_r76) 2019; 64 Paul (key20230726050507_r3) 2012; 403 key20230726050507_r54 Thiele (key20230726050507_r60) 2004; 101 key20230726050507_r53 Tzankov (key20230726050507_r79) 2022; 89 key20230726050507_r52 Tanaka-Okamoto (key20230726050507_r66) 2017; 27 key20230726050507_r51 key20230726050507_r50 key20230726050507_r49 key20230726050507_r48 Akama (key20230726050507_r63) 2000; 26 key20230726050507_r47 Yorifuji (key20230726050507_r81) 2018; 135 Waryah (key20230726050507_r61) 2016; 90 Soares da Costa (key20230726050507_r7) 2017; 19 Matsuda (key20230726050507_r67) 2019; 18 Guan (key20230726050507_r10) 2021; 25 Sanchez-Palencia (key20230726050507_r77) 2011; 129 key20230726050507_r46 key20230726050507_r45 key20230726050507_r44 Blanco (key20230726050507_r65) 2015; 54 Xiong (key20230726050507_r13) 2023; 12 key20230726050507_r43 key20230726050507_r42 Dündar (key20230726050507_r64) 2009; 85 key20230726050507_r41 key20230726050507_r40 Nuytemans (key20230726050507_r80) 2018; 161 Wang (key20230726050507_r71) 2021; 12 key20230726050507_r39 key20230726050507_r38 key20230726050507_r37 key20230726050507_r36 Muthana (key20230726050507_r2) 2012; 7 Jenniskens (key20230726050507_r57) 2006; 206 Bhattacharyya (key20230726050507_r70) 2020; 11 Brown (key20230726050507_r58) 2016; 134 Ito (key20230726050507_r78) 2017; 13 key20230726050507_r35 key20230726050507_r34 key20230726050507_r33 key20230726050507_r32 key20230726050507_r31 key20230726050507_r30 Bowman (key20230726050507_r5) 1999; 6 |
| References_xml | – ident: key20230726050507_r21 – volume: 54 start-page: 1236 year: 2015 ident: key20230726050507_r65 article-title: Improved prediction of knee osteoarthritis progression by genetic polymorphisms: the Arthrotest Study. publication-title: Rheumatology doi: 10.1093/rheumatology/keu478 contributor: fullname: Blanco – ident: key20230726050507_r40 – ident: key20230726050507_r29 – volume: 69 start-page: 9202 year: 2009 ident: key20230726050507_r74 article-title: Gene expression profiles in peripheral blood mononuclear cells can distinguish patients with non-small cell lung cancer from patients with nonmalignant lung disease. publication-title: Cancer Res doi: 10.1158/0008-5472.CAN-09-1378 contributor: fullname: Showe – ident: key20230726050507_r48 – ident: key20230726050507_r25 – ident: key20230726050507_r44 – volume: 11 start-page: 2327 year: 2020 ident: key20230726050507_r70 article-title: Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signalling, potentially impacting epithelial and mesenchymal identity. publication-title: Oncotarget doi: 10.18632/oncotarget.27634 contributor: fullname: Bhattacharyya – volume: 61 start-page: 1972 year: 2016 ident: key20230726050507_r68 article-title: CHST11/13 Regulate the Metastasis and Chemosensitivity of Human Hepatocellular Carcinoma Cells Via Mitogen-Activated Protein Kinase Pathway. publication-title: Dig Dis Sci doi: 10.1007/s10620-016-4114-5 contributor: fullname: Zhou – volume: 26 start-page: 237 year: 2000 ident: key20230726050507_r63 article-title: Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene. publication-title: Nat Genet doi: 10.1038/79987 contributor: fullname: Akama – ident: key20230726050507_r39 – volume: 41 start-page: 13117 year: 2002 ident: key20230726050507_r1 article-title: Carbohydrate sulfotransferases of the GalNAc/Gal/GlcNAc 6ST family. publication-title: Biochemistry doi: 10.1021/bi020507h contributor: fullname: Grunwell – ident: key20230726050507_r54 – ident: key20230726050507_r31 – ident: key20230726050507_r16 – ident: key20230726050507_r50 – ident: key20230726050507_r35 – ident: key20230726050507_r45 – volume: 91 start-page: 868 year: 2017 ident: key20230726050507_r56 article-title: Chondrodysplasia with Multiple Dislocations: Comprehensive Study of a Series of 30 Cases. publication-title: Clin Genet doi: 10.1111/cge.12885 contributor: fullname: Ranza – volume: 11 start-page: 2400 year: 2022 ident: key20230726050507_r75 article-title: CHST7 Methylation Status Related to the Proliferation and Differentiation of Pituitary Adenomas. publication-title: Cells doi: 10.3390/cells11152400 contributor: fullname: Dong – ident: key20230726050507_r20 – volume: 101 start-page: 10155 year: 2004 ident: key20230726050507_r60 article-title: Loss of chondroitin 6-O-sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement. publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0400334101 contributor: fullname: Thiele – volume: 6 start-page: 85 year: 2020 ident: key20230726050507_r11 article-title: Impairment of the autophagy-lysosomal pathway and activation of pyroptosis in macular corneal dystrophy. publication-title: Cell Death Discov doi: 10.1038/s41420-020-00320-z contributor: fullname: Zheng – volume: 129 start-page: 355 year: 2011 ident: key20230726050507_r77 article-title: Gene expression profiling reveals novel biomarkers in nonsmall cell lung cancer. publication-title: Int J Cancer doi: 10.1002/ijc.25704 contributor: fullname: Sanchez-Palencia – volume: 89 start-page: 81 year: 2022 ident: key20230726050507_r79 article-title: Increase in Chondroitin Sulfate and Decline in Arylsulfatase B May Contribute to Pathophysiology of COVID-19 Respiratory Failure. publication-title: Pathobiology doi: 10.1159/000519542 contributor: fullname: Tzankov – volume: 18 start-page: 4100 year: 2019 ident: key20230726050507_r67 article-title: Overexpression of carbohydrate sulfotransferase 15 in pancreatic cancer stroma is associated with worse prognosis. publication-title: Oncol Lett contributor: fullname: Matsuda – ident: key20230726050507_r49 – volume: 19 start-page: 1 year: 2017 ident: key20230726050507_r7 article-title: Sulfation of glycosamynoglycans and its implications in human health and disorders. publication-title: Annu Rev Biomed Eng doi: 10.1146/annurev-bioeng-071516-044610 contributor: fullname: Soares da Costa – ident: key20230726050507_r24 – ident: key20230726050507_r28 – ident: key20230726050507_r41 – volume: 64 start-page: 2158 year: 2019 ident: key20230726050507_r76 article-title: CHST7 Gene Methylation and Sex-Specific Effects on Colorectal Cancer Risk. publication-title: Dig Dis Sci doi: 10.1007/s10620-019-05530-9 contributor: fullname: Bi – volume: 403 start-page: 1491 year: 2012 ident: key20230726050507_r3 article-title: Recent advances in sulfotransferase enzyme activity assays. publication-title: Anal Bioanal Chem doi: 10.1007/s00216-012-5944-4 contributor: fullname: Paul – volume: 12 start-page: 4938 year: 2023 ident: key20230726050507_r13 article-title: Highly expressed carbohydrate sulfotransferase 11 correlates with unfavorable prognosis and immune evasion of hepatocellular carcinoma. publication-title: Cancer Med doi: 10.1002/cam4.5186 contributor: fullname: Xiong – ident: key20230726050507_r38 – ident: key20230726050507_r51 – volume: 206 start-page: 283 year: 2006 ident: key20230726050507_r57 article-title: Heparan sulfates in skeletal muscle development and physiology. publication-title: J Cell Physiol doi: 10.1002/jcp.20450 contributor: fullname: Jenniskens – ident: key20230726050507_r17 – ident: key20230726050507_r30 – volume: 25 start-page: 6006 year: 2021 ident: key20230726050507_r10 article-title: Carbohydrate sulfotransferase 3 (CHST3) overexpression promotes cartilage endplate‐derived stem cells (CESCs) to regulate molecular mechanisms related to repair of intervertebral disc degeneration by rat nucleus pulposus. publication-title: J Cell Mol Med doi: 10.1111/jcmm.16440 contributor: fullname: Guan – volume: 10 year: 2020 ident: key20230726050507_r12 article-title: Carbohydrate sulfotransferase 4 inhibits the progression of hepatitis B virus-related hepatocellular carcinoma and is a potential prognostic marker in several tumors. publication-title: Front Oncol contributor: fullname: Zhang – ident: key20230726050507_r34 – volume: 90 start-page: 90 year: 2016 ident: key20230726050507_r61 article-title: A novel CHST3 allele associated with spondyloepiphyseal dysplasia and hearing loss in Pakistani kindred. publication-title: Clin Genet doi: 10.1111/cge.12694 contributor: fullname: Waryah – volume: 12 start-page: 3934 year: 2021 ident: key20230726050507_r71 article-title: Knockdown of carbohydrate sulfotransferase 12 decreases the proliferation and mobility of glioblastoma cells via the WNT/β-catenin pathway. publication-title: Bioengineered doi: 10.1080/21655979.2021.1944455 contributor: fullname: Wang – volume: 23 start-page: 818 year: 2022 ident: key20230726050507_r55 article-title: Biallelic variants in CHST3 cause Spondyloepiphyseal dysplasia with joint dislocations in three Pakistani kindreds. publication-title: BMC Musculoskelet Disord doi: 10.1186/s12891-022-05719-6 contributor: fullname: Kausar – volume: 23 start-page: 12 year: 2014 ident: key20230726050507_r59 article-title: Craniosynostosis: a previously unreported association with CHST3-related skeletal dysplasia (autosomal recessive Larsen syndrome). publication-title: Clin Dysmorphol doi: 10.1097/MCD.0000000000000021 contributor: fullname: Searle – ident: key20230726050507_r42 – ident: key20230726050507_r23 – ident: key20230726050507_r46 – ident: key20230726050507_r27 – ident: key20230726050507_r33 – volume: 1820 start-page: 1306 year: 2012 ident: key20230726050507_r62 article-title: Diseases of glycosylation beyond classical congenital disorders of glycosylation. publication-title: Biochim Biophys Acta doi: 10.1016/j.bbagen.2012.02.001 contributor: fullname: Hennet – volume: 205 year: 2021 ident: key20230726050507_r69 article-title: Exploring the sulfate patterns of chondroitin sulfate/dermatan sulfate and keratan sulfate in human pancreatic cancer. publication-title: J Pharm Biomed Anal doi: 10.1016/j.jpba.2021.114339 contributor: fullname: Ren – ident: key20230726050507_r14 – volume: 85 start-page: 873 year: 2009 ident: key20230726050507_r64 article-title: Loss of dermatan-4-sulfotransferase 1 function results in adducted thumb-clubfoot syndrome. publication-title: Am J Hum Genet doi: 10.1016/j.ajhg.2009.11.010 contributor: fullname: Dündar – ident: key20230726050507_r37 – volume: 27 start-page: 400 year: 2017 ident: key20230726050507_r66 article-title: Various sulfated carbohydrate tumor marker candidates identified by focused glycomic analyses. publication-title: Glycobiology contributor: fullname: Tanaka-Okamoto – volume: 13 start-page: 4799 year: 2017 ident: key20230726050507_r78 article-title: Prognostic impact of carbohydrate sulfotransferase 15 in patients with pancreatic ductal adenocarcinoma. publication-title: Oncol Lett doi: 10.3892/ol.2017.6071 contributor: fullname: Ito – ident: key20230726050507_r18 – ident: key20230726050507_r52 – ident: key20230726050507_r22 – volume: 20 start-page: 3331 year: 2019 ident: key20230726050507_r9 article-title: The clinical potential of oligonucleotide therapeutics against pancreatic cancer. publication-title: Int J Mol Sci doi: 10.3390/ijms20133331 contributor: fullname: Takakura – volume: 11 start-page: 206 year: 1997 ident: key20230726050507_r4 article-title: Enzymology of human cytosolic sulfotransferases. publication-title: FASEB J doi: 10.1096/fasebj.11.4.9068609 contributor: fullname: Falany – ident: key20230726050507_r26 – volume: 6 start-page: R9 year: 1999 ident: key20230726050507_r5 article-title: Carbohydrate sulfotransferases: mediators of extracellular communication. publication-title: Chem Biol doi: 10.1016/S1074-5521(99)80014-3 contributor: fullname: Bowman – volume: 7 start-page: 31 year: 2012 ident: key20230726050507_r2 article-title: Modifications of glycans: biological significance and therapeutic opportunities. publication-title: ACS Chem Biol doi: 10.1021/cb2004466 contributor: fullname: Muthana – ident: key20230726050507_r47 – volume: 9 start-page: 10542 year: 2019 ident: key20230726050507_r6 article-title: Extracellular matrix composition of connective tissues: a systematic review and meta-analysis. publication-title: Sci Rep doi: 10.1038/s41598-019-46896-0 contributor: fullname: McKee – ident: key20230726050507_r43 – volume: 36 start-page: 9023 year: 2015 ident: key20230726050507_r72 article-title: Prognostic impact of chondroitin-4-sulfotransferase CHST11 in ovarian cancer. publication-title: Tumour Biol doi: 10.1007/s13277-015-3652-3 contributor: fullname: Oliveira-Ferrer – ident: key20230726050507_r32 – volume: 56 start-page: 1328 year: 2018 ident: key20230726050507_r73 article-title: Serum carbohydrate sulfotransferase 7 in lung cancer and non-malignant pulmonary inflammations. publication-title: Clin Chem Lab Med doi: 10.1515/cclm-2017-1157 contributor: fullname: Debeljak – ident: key20230726050507_r15 – volume: 135 start-page: 259 year: 2018 ident: key20230726050507_r81 article-title: CHST3 and CHST13 polymorphisms as predictors of bosentan-induced liver toxicity in Japanese patients with pulmonary arterial hypertension. publication-title: Pharmacol Res doi: 10.1016/j.phrs.2018.08.011 contributor: fullname: Yorifuji – volume: 161 start-page: 43 year: 2018 ident: key20230726050507_r80 article-title: Variants in chondroitin sulfate metabolism genes in thrombotic storm. publication-title: Thromb Res doi: 10.1016/j.thromres.2017.11.016 contributor: fullname: Nuytemans – ident: key20230726050507_r53 – volume: 11 start-page: 512 year: 2020 ident: key20230726050507_r8 article-title: Versican-A critical extracellular matrix regulator of immunity and inflammation. publication-title: Front Immunol doi: 10.3389/fimmu.2020.00512 contributor: fullname: Wight – ident: key20230726050507_r19 – ident: key20230726050507_r36 – volume: 134 start-page: 485 year: 2016 ident: key20230726050507_r58 article-title: Emerging tools to study proteoglycan function during skeletal development. publication-title: Methods Cell Biol doi: 10.1016/bs.mcb.2016.03.001 contributor: fullname: Brown |
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| Title | Carbohydrate sulfotransferases: a review of emerging diagnostic and prognostic applications |
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