Mango ‘criollo’ by-products as a source of polyphenols with antioxidant capacity. Ultrasound assisted extraction evaluated by response surface methodology and HPLC-ESI-QTOF-MS/MS characterization

• Published in: Food chemistry Vol. 396; p. 133738
• Main Authors: Ojeda, Gonzalo Adrián, Sgroppo, Sonia Cecilia, Sánchez-Moreno, Concepción, de Ancos, Begoña
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01-12-2022
• Subjects: HPLC-MS/MS; Mangiferin; Polyphenols; Quercetin derivatives; RSM; Isoquercitrin (PubChem CID: 5280804); Penta-O-galloyl glucose (PubChem CID: 65238); Ethyl gallate (PubChem CID: 13250); RSM; Ellagic acid (PubChem CID: 5281855); Mangiferin (PubChem CID: 5281647); HPLC-MS/MS; Quercitrin (PubChem CID: 5280459); Quercetin-3-O-galactoside (PubChem CID: 5281643); Polyphenols; Isomangiferin (PubChem CID: 5318597); Quercetin derivatives; Mangiferin
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2022.133738

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•Conditions to maximize phenolic extraction differ among mango fruit section.•Optimization of the process reduces solvent utilization and time operation.•Mango ‘criollo’ by products are a rich source of bioactive compounds.•Ultrasound assisted extraction enhances mangiferin and ellagic acid recovery.
Ultrasound assisted extraction (UAE) was evaluated as a green procedure for the recovery of phenolic compounds with antioxidant capacity from underutilized mango 'criollo' (peel, pulp and seed). Magnetic stirred was performed as conventional extraction. Response surface methodology using a three-factor (% ethanol, amplitude and time) central composite design was used to maximize the extraction for total phenolic compounds (TPC), total flavonoids and antioxidant capacity. The operational conditions to maximize extraction were: peel, 46% ethanol/amplitude 60% (36 µm)/6.5 min; pulp, 25% ethanol/amplitude 75% (45 µm)/30 min; seed 49% ethanol/100% (60 µm) amplitude/20 min. The phenolic composition of the optimized extracts was characterized by HPLC-QTOF-MS/MS and 45 compounds were tentatively identified as xanthones (mangiferin), flavonoids (quercetin), ellagic acid, benzophenones (maclurin), gallate derivatives and gallotannins. UAE increased TPC extraction (33%); interestingly mangiferin extraction increased 53% in peel, similarly, ellagic acid increased up to 2.5 and 4.4 times in peel and seed extracts.