Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging

An ultrasmall superparamagnetic iron oxide (USPIO) preparation was evaluated as a potential intravenous contrast agent for lymph nodes. Relaxation time measurements and magnetic resonance (MR) imaging were performed in rats with normal lymph nodes and in rats with lymph node metastases. In normal an...

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Bibliographic Details
Published in:	Radiology Vol. 175; no. 2; p. 494
Main Authors:	Weissleder, R, Elizondo, G, Wittenberg, J, Lee, A S, Josephson, L, Brady, T J
Format:	Journal Article
Language:	English
Published:	United States 01-05-1990
Subjects:	Animals Contrast Media Dose-Response Relationship, Drug Ferrosoferric Oxide Injections, Intravenous Iron - administration & dosage Iron - pharmacokinetics Liver Neoplasms, Experimental Lymph Nodes - metabolism Lymph Nodes - pathology Lymphatic Metastasis - pathology Magnetic Resonance Imaging Male Oxides Particle Size Rats Rats, Inbred Strains
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