Natural and semi-synthetic clerodanes of Croton cajucara and their cytotoxic effects against ehrlich carcinoma and human K562 leukemia cells

The clerodane-type diterpene, trans-dehydrocrotonin (1) the major component of Croton cajucara has shown striking correlation with its therapeutic use in traditional folk medicine. Phytochemical investigations led to the isolation of the metabolites 1, cajucarinolide (6), isocajucarinolide (7), tran...

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Bibliographic Details

Published in:	Journal of the Brazilian Chemical Society Vol. 18; no. 2; pp. 391 - 396
Main Authors:	Maciel, Maria Aparecida M., Martins, Jenilce R., Pinto, Angelo C., Kaiser, Carlos R., Esteves-Souza, Andressa, Echevarria, Aurea
Format:	Journal Article
Language:	English
Published:	Sociedade Brasileira de Química 01-04-2007
Subjects:	CHEMISTRY, MULTIDISCIPLINARY trans-dehydrocrotonin isocajucarinolide cytotoxic activity Croton cajucara cajucarinolide
Online Access:	Get full text
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