Comparison of oral cholecystopaques: iopronic acid vs. iopanoic acid

A new oral cholecystopaque, iopronic acid, was compared to iopanoic acid. This was a double blind, randomized study of 260 subjects. A 4.5-G dose of iopronic acid produced a similar degree of gallbladder opacification as 3.0 g of iopanoic acid. Adverse reactions to the contrast media were generally...

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Bibliographic Details
Published in:	Radiology Vol. 134; no. 1; p. 31
Main Authors:	Amberg, J R, Goldberger, L A, Bates, M
Format:	Journal Article
Language:	English
Published:	United States 01-01-1980
Subjects:	Cholecystography Clinical Trials as Topic Contrast Media - adverse effects Double-Blind Method Humans Iodobenzenes - adverse effects Iopanoic Acid - adverse effects Random Allocation
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Summary:	A new oral cholecystopaque, iopronic acid, was compared to iopanoic acid. This was a double blind, randomized study of 260 subjects. A 4.5-G dose of iopronic acid produced a similar degree of gallbladder opacification as 3.0 g of iopanoic acid. Adverse reactions to the contrast media were generally mild, but were significantly less with iopronic acid. The present study is criticized because it was not designed to help the radiologist determine the better contrast medium under optimal clinical conditions.
ISSN:	0033-8419
DOI:	10.1148/radiology.134.1.6985742