Synthesis of new ibuprofen hybrid conjugates as potential anti-inflammatory and analgesic agents

A new set of hybrid conjugates derived from 2-(4-isobutylphenyl)propanoic acid (ibuprofen) is synthesized to overcome the drawbacks of the current non-steroidal anti-inflammatory drugs. Synthesized conjugates were screened for their anti-inflammatory, analgesic and ulcerogenic properties. Few conjug...

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Bibliographic Details

Published in:	Future medicinal chemistry Vol. 12; no. 15; pp. 1369 - 1386
Main Authors:	Panda, Siva S, Girgis, Adel S, Honkanadavar, Hitesh H, George, Riham F, Srour, Aladdin M
Format:	Journal Article
Language:	English
Published:	England Newlands Press Ltd 01-08-2020
Subjects:	acetaminophen analgesic anti-inflammatory cyclooxygenase molecular modeling NSAIDs anti-inflammatory cyclooxygenase acetaminophen analgesic molecular modeling NSAIDs
Online Access:	Get full text
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