Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer

Predicting response to endocrine therapy and survival in oestrogen receptor positive breast cancer is a significant clinical challenge and novel prognostic biomarkers are needed. Long-range regulators of gene expression are emerging as promising biomarkers and therapeutic targets for human diseases,...

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Bibliographic Details
Published in:	Human molecular genetics Vol. 25; no. 15; pp. 3269 - 3283
Main Authors:	Milevskiy, Michael J G, Al-Ejeh, Fares, Saunus, Jodi M, Northwood, Korinne S, Bailey, Peter J, Betts, Joshua A, McCart Reed, Amy E, Nephew, Kenneth P, Stone, Andrew, Gee, Julia M W, Dowhan, Dennis H, Dray, Eloise, Shewan, Annette M, French, Juliet D, Edwards, Stacey L, Clark, Susan J, Lakhani, Sunil R, Brown, Melissa A
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01-08-2016
Subjects:	Biomarkers, Tumor - biosynthesis Biomarkers, Tumor - genetics Breast Neoplasms - drug therapy Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Female Forkhead Box Protein M1 - biosynthesis Forkhead Box Protein M1 - genetics Gene Expression Regulation, Neoplastic Hepatocyte Nuclear Factor 3-alpha - biosynthesis Hepatocyte Nuclear Factor 3-alpha - genetics Humans MCF-7 Cells Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics RNA, Long Noncoding - biosynthesis RNA, Long Noncoding - genetics RNA, Neoplasm - biosynthesis RNA, Neoplasm - genetics Transcription, Genetic
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