Detection of putative autoantibodies in systemic lupus erythematous using a novel native-conformation protein microarray platform

Objective Conventional immunoassays detect autoantibodies related to systemic lupus erythematosus (SLE) via recognition of epitopes on autoantigens expressed in their denatured rather than native conformational state, casting difficulty in evaluating the genuine pathogenicity of the autoantibodies....

Full description

Saved in:

Bibliographic Details
Published in:	Lupus Vol. 29; no. 14; pp. 1948 - 1954
Main Authors:	Mak, Anselm, Kow, Nien Yee, Ismail, Nur Hafiza, Anuar, Nur Diana, Rutt, Nurul H, Cho, Jiacai, Rosli, Nurul Shielawati Binti Mohamed, Dharmahidari, Bhushan
Format:	Journal Article
Language:	English
Published:	London, England SAGE Publications 01-12-2020 Sage Publications Ltd
Subjects:	Autoantibodies Autoantigens Bioinformatics Chromatin DNA microarrays Epitopes Gene regulation Lupus NF-κB protein Pathogenicity Protein arrays Protein structure Proteins Systemic lupus erythematosus Transcription Autoantibody lupus proteins high-throughput microarrays
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!