The antinociceptive effect of moclobemide on the vocalization threshold to paw pressure in a rat model of unilateral mononeuropathy

The aim of our study was to investigate the antinociceptive activity of moclobemide on the vocalization threshold to paw pressure in a rat model of unilateral mononeuropathy. The neuropathy was produced by ligation of the sciatic nerve and nociceptive thresholds were determined 15–21 days after surg...

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Bibliographic Details

Published in:	Pharmacological research Vol. 44; no. 6; pp. 503 - 507
Main Authors:	Apaydin, Sebnem, Goldeli, Esin, Uyar, Meltem, Erhan, Elvan, Yegul, Ibrahim, Tuglular, Isik
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01-12-2001
Subjects:	Analgesics - pharmacology Animals Hindlimb Male Moclobemide - pharmacology moclobemide, antinociceptive effect, sciatic nerve ligation, paw pressure, rat Monoamine Oxidase Inhibitors - pharmacology Pain Threshold - drug effects Physical Stimulation Rats Rats, Wistar Sciatic Neuropathy - drug therapy Sciatic Neuropathy - physiopathology Vocalization, Animal - drug effects moclobemide, antinociceptive effect, sciatic nerve ligation, paw pressure, rat
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