Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum

Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum

Two endogenous differentiation-inducing factors (DIF-2 and DIF-3), which induce stalk-cell differentiation in the cellular slime mould Dictyostelium discoideum, have been identified as the pentan-1-one and monochloro analogues respectively of (1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-...

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Bibliographic Details
Published in:Biochemical journal Vol. 249; no. 3; pp. 903 - 906
Main Authors: Morris, H.R, Masento, M.S, Taylor, G.W, Jermyn, K.A, Kay, R.R
Format: Journal Article
Language:English
Published: England 01-02-1988
Subjects:
cell biology
Cell Differentiation
cells
Chemical Phenomena
chemical structure
Chemistry
Dictyostelium
Dictyostelium - analysis
Dictyostelium discoideum
differentiation
effector molecules
Hexanones
Ketones
Mass Spectrometry
molds
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Summary:Two endogenous differentiation-inducing factors (DIF-2 and DIF-3), which induce stalk-cell differentiation in the cellular slime mould Dictyostelium discoideum, have been identified as the pentan-1-one and monochloro analogues respectively of (1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one). These compounds represent a new chemical class of effector molecules.
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ISSN:0264-6021
1470-8728
DOI:10.1042/bj2490903