Weinreb amide as an efficient reagent in the one pot synthesis of benzimidazoles and benzothiazoles

One pot synthesis of 2-substituted benzimidazoles/benzothiazoles through condensation is followed by cyclization of Weinreb amide with o-diaminoarene or o-aminothiophenol is reported. In the presence of boron trifluoride etherate in 1,4-dioxane solvent, a high yield (75–94%) was achieved within 60mi...

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Bibliographic Details
Published in:	Tetrahedron letters Vol. 54; no. 21; pp. 2693 - 2695
Main Authors:	Bommegowda, Yadaganahalli K., Lingaraju, Gejjalagere S., Thamas, Saji, Vinay Kumar, Koravangala S., Pradeepa Kumara, Challanayakanahally S., Rangappa, Kanchugarakoppal S., Sadashiva, Marilinganadoddi P.
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 22-05-2013
Subjects:	Amides Benzimidazoles Benzothiazoles Boron Boron trifluoride etherate Condensing Functional groups Halogens o-Aminothiophenol o-Diaminoarene Solvents Synthesis (chemistry) Tetrahedrons Weinreb amide Benzimidazoles Weinreb amide Boron trifluoride etherate o-Diaminoarene Benzothiazoles o-Aminothiophenol
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