Formal synthesis of (+)-crocacin C

The formal synthesis of (+)-crocacin C is reported. The approach described takes advantage of a highly regioselective epoxide cuprate addition and a diastereoselective Overman rearrangement. The synthesis is practical and amenable to scale up.

Bibliographic Details

Published in:	Tetrahedron letters Vol. 53; no. 16; pp. 2114 - 2116
Main Authors:	Pasqua, Adele E., Ferrari, Frank D., Crawford, James J., Marquez, Rodolfo
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 18-04-2012
Subjects:	COPPER OXIDE Crocacins Cuprates FABRICATION Formal synthesis Overman rearrangement Synthesis (chemistry) Tetrahedrons Formal synthesis Crocacins Overman rearrangement
Online Access:	Get full text
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