Small footprint liquid chromatography-mass spectrometry for pharmaceutical reaction monitoring and automated process analysis

•Small footprint LC-UV/MS system for pharmaceutical process monitoring.•In-fumehood reaction monitoring by LC-UV/MS.•Automated sample dilution, derivatisation, and delivery.•Multi-deep LED based absorbance detection with portable mass spectrometry. Liquid chromatography (LC) has broad applicability...

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Bibliographic Details

Published in:	Journal of Chromatography A Vol. 1656; p. 462545
Main Authors:	Hemida, Mohamed, Haddad, Paul R., Lam, Shing C., Coates, Lewellwyn J., Riley, Frank, Diaz, Angel, Gooley, Andrew A., Wirth, Hans-Jürgen, Guinness, Steven, Sekulic, Sonja, Paull, Brett
Format:	Journal Article
Language:	English
Published:	Elsevier B.V 25-10-2021
Subjects:	Absorbance detectors Capillary liquid chromatography Miniaturization Portable mass spectrometry Process analytical technologies Process analytical technologies Miniaturization Absorbance detectors Capillary liquid chromatography Portable mass spectrometry
Online Access:	Get full text
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