Quinacrine in the management of malignant pleural effusion

Twenty-five patients with malignant pleural effusion were treated with a single intrapleural dose of Quinacrine. Eighteen patients (72 per cent) had a significant response, with no reaccumulation of fluid for at least 2 months following treatment up to a maximum of 18 months in 2 patients. Seven pat...

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Bibliographic Details
Published in:	British journal of surgery Vol. 64; no. 1; p. 52
Main Authors:	Taylor, S A, Hooton, N S, Macarthur, A M
Format:	Journal Article
Language:	English
Published:	England 01-01-1977
Subjects:	Breast Neoplasms - drug therapy Bronchial Neoplasms - drug therapy Female Humans Pleural Effusion - drug therapy Pleural Neoplasms - drug therapy Quinacrine - therapeutic use
Online Access:	Get more information
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Summary:	Twenty-five patients with malignant pleural effusion were treated with a single intrapleural dose of Quinacrine. Eighteen patients (72 per cent) had a significant response, with no reaccumulation of fluid for at least 2 months following treatment up to a maximum of 18 months in 2 patients. Seven patients (28 per cent) survived for longer than 1 year without evidence of recurrent effusion.
ISSN:	0007-1323
DOI:	10.1002/bjs.1800640113