Serum Apelin Levels and Ascending Aortic Aneurysm in Adults

• Published in: Indian journal of surgery Vol. 83; no. 4; pp. 881 - 884
• Main Authors: Yalcin, Mihriban, Yumun, Gündüz, Yilmaz, Ahsen, Kalafat, Hakan, Guzel, Savaş
• Format: Journal Article
• Language: English
• Published: New Delhi Springer India 01-08-2021; Springer; Springer Nature B.V
• Subjects: Aortic aneurysms; Cardiac Surgery; Comparative analysis; Enzyme-linked immunosorbent assay; Medical research; Medicine; Medicine & Public Health; Medicine, Experimental; Neurosurgery; Original Article; Pediatric Surgery; Plastic Surgery; Surgery; Thoracic Surgery; Ascending aortic aneurysm; Adult; Apelin receptor; Apelin
• ISSN: 0972-2068; 0973-9793
• DOI: 10.1007/s12262-020-02440-3

Apelin is a peptide isolated from bovine stomach and has vasodilator and inotropic activities. The aim of this study was to confirm the relationship between serum apelin levels and ascending aortic dilatation in adult patients. This study included 39 patients with ascending aortic aneurysm who applied to the cardiovascular surgery outpatient clinic between 1 June 2019 and 31 August 2019 and 50 healthy volunteers. Serum apelin and serum apelin receptor levels were measured with ELISA method. Serum apelin levels were lower in patients with aortic aneurysm compared to the control group, while serum apelin receptor levels were higher. These findings may show that serum apelin and apelin receptor levels may be a potential biomarker for aortic aneurysm.