Steroids and serum complement in mice: influence of hydrocortisone, diethylstilbestrol, and testosterone

Hydrocortisone depresses hemnolytic complement in male and female mice. Testosterone causes increase of serum complement in female mice, and diethylstilbestrol causes decrease of serum complement in male mice, in each instance to activities approximating those found normally in the opposite sex. Mal...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) Vol. 152; no. 3723; pp. 782 - 783
Main Authors: Caren, L D, Rosenberg, L T
Format: Journal Article
Language:English
Published: United States 06-05-1966
Online Access:Get full text
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Summary:Hydrocortisone depresses hemnolytic complement in male and female mice. Testosterone causes increase of serum complement in female mice, and diethylstilbestrol causes decrease of serum complement in male mice, in each instance to activities approximating those found normally in the opposite sex. Male and female sex hormones have no effect, in the doses used, on the serum complement of male and female mice respectively.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0036-8075
1095-9203
DOI:10.1126/science.152.3723.782