A Case of Erythroderma Secondary to Hypereosinophilia

Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to eosinophilia without secondary cause. Early recognition and treatment are essential to prevent morbidity and mortality. Cytoreduction with Steroids,...

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Published in:Journal of clinical and diagnostic research Vol. 10; no. 5; pp. OD15 - OD16
Main Authors: Abdulsalam, Mohammed Shafi, Ghanta, Hari Chandana, Pandurangan, Prabu, Menon, Maya, Jacob, Sheba S K
Format: Journal Article
Language:English
Published: India JCDR Research and Publications Private Limited 01-05-2016
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Abstract Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to eosinophilia without secondary cause. Early recognition and treatment are essential to prevent morbidity and mortality. Cytoreduction with Steroids, Hydroxyurea and Imatinib are the main stay of treatment. Molecular studies like Fip1-like-1 fused with platelet derived growth factor receptor alpha (FIP1L1-PDGFRα) etc., are recommended in view of therapeutic implication. In this paper we report a rare case of HES developing in a lady 6 months after surgical removal of lymphangioma of spleen, which in itself is rare.
AbstractList Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to eosinophilia without secondary cause. Early recognition and treatment are essential to prevent morbidity and mortality. Cytoreduction with Steroids, Hydroxyurea and Imatinib are the main stay of treatment. Molecular studies like Fip1-like-1 fused with platelet derived growth factor receptor alpha (FIP1L1-PDGFRα) etc., are recommended in view of therapeutic implication. In this paper we report a rare case of HES developing in a lady 6 months after surgical removal of lymphangioma of spleen, which in itself is rare.
Author Abdulsalam, Mohammed Shafi
Menon, Maya
Jacob, Sheba S K
Ghanta, Hari Chandana
Pandurangan, Prabu
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  givenname: Mohammed Shafi
  surname: Abdulsalam
  fullname: Abdulsalam, Mohammed Shafi
  organization: Post Graduate Student, Department of Internal Medicine, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India
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  givenname: Hari Chandana
  surname: Ghanta
  fullname: Ghanta, Hari Chandana
  organization: Associate Consultant Physician, Department of Internal Medicine, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India
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  givenname: Prabu
  surname: Pandurangan
  fullname: Pandurangan, Prabu
  organization: Consultant Haematologist, Department of Haematology, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India
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  givenname: Maya
  surname: Menon
  fullname: Menon, Maya
  organization: Senior Consultant Pathologist, Department of Pathology, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India
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  givenname: Sheba S K
  surname: Jacob
  fullname: Jacob, Sheba S K
  organization: Consultant Pathologist, Department of Pathology, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India
BackLink https://www.ncbi.nlm.nih.gov/pubmed/27437281$$D View this record in MEDLINE/PubMed
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Keywords Cytoreduction
Lymphangioma of spleen
Adrenal insufficiency
Tissue eosinophilia
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Snippet Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to...
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SubjectTerms adrenal insufficiency
cytoreduction
lymphangioma of spleen
tissue eosinophilia
Title A Case of Erythroderma Secondary to Hypereosinophilia
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