A Case of Erythroderma Secondary to Hypereosinophilia
Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to eosinophilia without secondary cause. Early recognition and treatment are essential to prevent morbidity and mortality. Cytoreduction with Steroids,...
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Published in: | Journal of clinical and diagnostic research Vol. 10; no. 5; pp. OD15 - OD16 |
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JCDR Research and Publications Private Limited
01-05-2016
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Abstract | Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to eosinophilia without secondary cause. Early recognition and treatment are essential to prevent morbidity and mortality. Cytoreduction with Steroids, Hydroxyurea and Imatinib are the main stay of treatment. Molecular studies like Fip1-like-1 fused with platelet derived growth factor receptor alpha (FIP1L1-PDGFRα) etc., are recommended in view of therapeutic implication. In this paper we report a rare case of HES developing in a lady 6 months after surgical removal of lymphangioma of spleen, which in itself is rare. |
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AbstractList | Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to eosinophilia without secondary cause. Early recognition and treatment are essential to prevent morbidity and mortality. Cytoreduction with Steroids, Hydroxyurea and Imatinib are the main stay of treatment. Molecular studies like Fip1-like-1 fused with platelet derived growth factor receptor alpha (FIP1L1-PDGFRα) etc., are recommended in view of therapeutic implication. In this paper we report a rare case of HES developing in a lady 6 months after surgical removal of lymphangioma of spleen, which in itself is rare. |
Author | Abdulsalam, Mohammed Shafi Menon, Maya Jacob, Sheba S K Ghanta, Hari Chandana Pandurangan, Prabu |
Author_xml | – sequence: 1 givenname: Mohammed Shafi surname: Abdulsalam fullname: Abdulsalam, Mohammed Shafi organization: Post Graduate Student, Department of Internal Medicine, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India – sequence: 2 givenname: Hari Chandana surname: Ghanta fullname: Ghanta, Hari Chandana organization: Associate Consultant Physician, Department of Internal Medicine, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India – sequence: 3 givenname: Prabu surname: Pandurangan fullname: Pandurangan, Prabu organization: Consultant Haematologist, Department of Haematology, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India – sequence: 4 givenname: Maya surname: Menon fullname: Menon, Maya organization: Senior Consultant Pathologist, Department of Pathology, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India – sequence: 5 givenname: Sheba S K surname: Jacob fullname: Jacob, Sheba S K organization: Consultant Pathologist, Department of Pathology, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27437281$$D View this record in MEDLINE/PubMed |
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Title | A Case of Erythroderma Secondary to Hypereosinophilia |
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